Novel and known morbidities of leukodystrophies identified using a phenome-wide association study

Conclusions PheWAS analysis from a national database demonstrates shared and unique features of leukodystrophies. Developmental delay, cardiac dysrhythmias, fluid and electrolyte disturbances, and respiratory issues were common to all 4 leukodystrophy diseases. Use of a PheWAS in leukodystrophies and other pediatric neurologic diseases offers a method for targeting improved care for patients by identification of morbidities.
Source: Neurology Clinical Practice - Category: Neurology Authors: Tags: All Medical/Systemic disease, Leukodystrophies, All Pediatric, All Demyelinating disease (CNS) Research Source Type: research