Cortisone Acetate vs Hydrocortisone in Adrenal Insufficiency Cortisone Acetate vs Hydrocortisone in Adrenal Insufficiency
What impact might these treatments have on the metabolic profiles of patients with secondary adrenal insufficiency?Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 1, 2021 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Guidance to support implementation of NHS Steroid Emergency Card coming soon
Recently published guidance on the prevention and emergency management of adult patients with adrenal insufficiency outlined the general management issues relating to adrenal crisis. This was subsequently supported by an NHS England and NHS Improvement national patient safety alert (NatPSA) promoting the use of a new Steroid Emergency Card. The NatPSA specified a number of actions that organisations need to implement, to operationalise the introduction of the new Steroid Emergency Card. The NHS has been asked to implement this alert by May 2021. However, it has become clear that many groups need support o...
Source: Society for Endocrinology - December 23, 2020 Category: Endocrinology Source Type: news

Glucocorticoid management approaches vary for patients with adrenal insufficiency taking COVID-19 vaccine
The Pituitary Society present results from a survey on the COVID-19 vaccine and approaches to glucocorticoid management in patients with adrenal insufficiency.European Society of Endocrinology (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 22, 2020 Category: Endocrinology Source Type: news

New Paediatric Steroid Treatment Card for adrenal insufficiency
The newBSPED Paediatric Steroid Treatment Card provides a succinct steroid management plan for illnesses, emergency injections and blood sugar& electrolyte correction.Please encourage your patients todownload and use this card.BSPED is keen to encourage uniform practice and improve the care of children and young people with adrenal insufficiency.If you have any queries regarding the card please contact theBSPED Clinical Committee. Learn more about managingadrenal crisis. (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 4, 2020 Category: Endocrinology Source Type: news

Computer vision predicts congenital adrenal hyperplasia
(University of Southern California) Using computer vision, researchers have discovered strong correlations between facial morphology and congenital adrenal hyperplasia (CAH), a life-threatening genetic condition of the adrenal glands and one of the most common forms of adrenal insufficiency in children. The findings could have implications for phenotyping and treating patients with CAH. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - November 18, 2020 Category: International Medicine & Public Health Source Type: news

Adrenal Insufficiency in Coronavirus Disease 2019 Adrenal Insufficiency in Coronavirus Disease 2019
This case of a COVID-19 patient with vasopressor-resistant hypotension highlights the need to be aware of acute adrenal insufficiency as a non-respiratory presentation of SARS-CoV-2 infection.Journal of Medical Case Reports (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 22, 2020 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news

Prevention of Adrenal Crisis Prevention of Adrenal Crisis
What is the most appropriate hydrocortisone dose and delivery mode to prevent adrenal crisis among patients with adrenal insufficiency?Journal of Clinical Endocrinology & Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - September 17, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Skin lightening creams may increase risk of adrenal insufficiency
Women who misuse corticosteroid creams for cosmetic skin lightening may be at risk of developing adrenal insufficiency, according to research presented at the European Society of Endocrinology’s digital Congress, e-ECE 2020.Times Now News (Source: Society for Endocrinology)
Source: Society for Endocrinology - September 11, 2020 Category: Endocrinology Source Type: news

New guidance for managing adrenal insufficiency
Newly published guidance for the prevention and emergency management of adrenal insufficiency in adults has been published in the Clinical Medicine Journal. The UK’s NHS has issued a Steroid Emergency Card and a National Patient Alert to support this.Medscape (Source: Society for Endocrinology)
Source: Society for Endocrinology - August 26, 2020 Category: Endocrinology Source Type: news

Stress Dosing Effects in Children With Adrenal Insufficiency Stress Dosing Effects in Children With Adrenal Insufficiency
A new study examines the effects of patient-initiated glucocorticoid stress dosing among children with congenital adrenal hyperplasia presenting with acute illness.Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 18, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

National Patient Safety Alert issued for NHS Steroid Emergency Card
ANational Patient Safety Alert has been issued asking providers to ensure all eligible patients with adrenal insufficiency are issued with anNHS Steroid Emergency Card, to support early recognition and treatment of adrenal crisis in adults. The alert requires that processes are put in place to check if a patient has an NHS Steroid Emergency Card ahead of any emergency treatment, elective surgery, or other invasive procedures.  This has been sent via the Central Alerting System to all NHS acute and community providers, including GPs and ambulance trusts, and will filter through over the n...
Source: Society for Endocrinology - August 13, 2020 Category: Endocrinology Source Type: news

NHS Steroid Emergency Card for adrenal insufficiency patients is available to order
Together with the Royal College of Physicians patient safety committee and the NHSE/I patient safety team we have developed a newNHS Steroid Emergency Card for adrenal insufficiency patients. It is an NHS wide card (England and the devolved nations) supported by this recently publishedGuidance. All is now in place and the NHS Steroid Emergency card is now available to order from 18 August 2020. As this is a new card various organisations across the NHS are working together to enable implementation. The new cards will need to be ordered so there may be a wait until cards are physically in stock and available to be ...
Source: Society for Endocrinology - August 13, 2020 Category: Endocrinology Source Type: news

Advice on COVID-19 and dexamethasone steroid treatment
A new clinical trial reports that glucocorticoid, dexamethasone, is effective for treating severe COVID-19. We want to assure people that this medicine should only be taken on prescription and under the care of a doctor.Glucocorticoids are a type of anti-inflammatory medicine used to treat a range of conditions such as allergies, asthma, eczema, inflammatory bowel disease, arthritis and the endocrine condition, adrenal insufficiency. Glucocorticoids can have serious side effects and should not be taken unless necessary.Dexamethasone was reportedly only effective in COVID-19 patients on ventilators or oxygen therapy, was of...
Source: Society for Endocrinology - June 18, 2020 Category: Endocrinology Source Type: news

Perioperative Glucocorticoids in Adrenal Insufficiency Perioperative Glucocorticoids in Adrenal Insufficiency
What is the optimal dosing for perioperative glucocorticoid administration in patients with adrenal insufficiency? This commentary explores the issue.Journal of Clinical Endocrinology & Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 12, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

A study of serum cortisol levels in acute head injury patients - Rao TP.
Introduction Adrenal insufficiency has a great impact on the prognosis of patients with traumatic brain injury. In healthy persons during normal day-to-day activity, the concentration of plasma cortisol is high in the morning, decreases during the day and ... (Source: SafetyLit)
Source: SafetyLit - June 2, 2020 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news

NHS Emergency Steroid Card for adrenal insufficiency patients released
To keep patients with adrenal insufficiency safe during the COVID-19 crisis NHSE&I have agreed it is appropriate to release theNHS Emergency Steroid Card as a PDF that patients can download themselves.Guidance related to the release of the new NHS Emergency Steroid Card is almost ready for publication but the COVID-19 crisis has taken precedence.The card can be downloaded from ouradrenal crisis webpage, where you will also find additional emergency adrenal insufficiency management information and COVID-19 guidance.    (Source: Society for Endocrinology)
Source: Society for Endocrinology - March 19, 2020 Category: Endocrinology Source Type: news

Spring issue of The Endocrinologist now available online
The spring issue of the Society’s quarterly magazineThe Endocrinologist is now available online.  This issue, with the theme,'Exercise: It's good to move it, move it' examines multiple benefits of staying active, including maintaining a healthy metabolism, improving bone health and staying well during aging and pregnancy.In Society News, find out all you ever wanted to know about your new Society President, Raj Thakker, learn about the Society's new Undergraduate Video Award, and read new Society guidance on peri-operative management of adrenal insufficiency.Browse this ...
Source: Society for Endocrinology - March 12, 2020 Category: Endocrinology Source Type: news

New guidelines for the management of adrenal insufficiency published
The Society for Endocrinology, the Association of Anaesthetists and the Royal College of Physicians have published newGuidelines for the management of glucocorticoids during the peri-operative period for patients with adrenal insufficiency.You can access the guidelines from theAnaesthesia journal website.The guidelines provide eight recommendations and aim to ensure that patients with adrenal insufficiency are identified and adequately supplemented with glucocorticoids during the peri-operative period.  Anaesthetists must be familiar with the symptoms and signs of acute adrenal insufficiency so that inade...
Source: Society for Endocrinology - February 4, 2020 Category: Endocrinology Source Type: news

Sport-related concussion preceding adrenal insufficiency and hypopituitarism - Northam WT, Alexander A, Carneiro K.
A 49-year-old female with history of daily inhaled corticosteroid use for asthma presented to a concussion clinic 7 wk after sport-related head injury with headache, visual blurring, dizziness, nausea, fatigue, polydipsia, and polyuria. Examination reveale... (Source: SafetyLit)
Source: SafetyLit - January 13, 2020 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Primary Adrenal Insufficiency: New Genetic Causes Primary Adrenal Insufficiency: New Genetic Causes
A new review provides insight into the genetics of primary adrenal insufficiency that can have implications for the management of this condition.Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 6, 2020 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Evaluating the Low-Dose ACTH Stimulation Test in Children Evaluating the Low-Dose ACTH Stimulation Test in Children
Low-dose ACTH stimulation tests are commonly used to diagnose central adrenal insufficiency. What are the optimal times for testing cortisol levels?Journal of Clinical Endocrinology & Metabolism (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 19, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Serum Interpretation in Suspected Adrenal Insufficiency Serum Interpretation in Suspected Adrenal Insufficiency
What role does a single measurement of serum cortisol have in the investigation of adrenal insufficiency? Could it help identify which patients require further testing?Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - November 5, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Daily Adjustment of Glucocorticoids in Adrenal Insufficiency Daily Adjustment of Glucocorticoids in Adrenal Insufficiency
Under what circumstances should daily dose adjustments be initiated in patients with adrenal insufficiency?Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 15, 2019 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Avoiding severe complications of postoperative adrenal insufficiency
The use of adrenalectomy in treatment of primary aldosterone can lead to persistent adrenal insufficiency, so postoperative adrenocorticotropic hormone stimulation testing is recommended to avoid adrenal crisis, according to German research published inThe Journal of Clinical Endocrinology& Metabolism.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - July 3, 2019 Category: Endocrinology Source Type: news

Hidden in the Epidemic: Opioid-Induced Adrenal Insufficiency Hidden in the Epidemic: Opioid-Induced Adrenal Insufficiency
Findings point to the need to screen adrenal function of chronic opioid users.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - April 30, 2019 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Mayo Clinic Q and A: Understanding adrenal insufficiency
DEAR MAYO CLINIC: What is adrenal insufficiency? Is it the same as Addison's disease? ANSWER: There are a few forms of adrenal insufficiency, which is an uncommon disorder caused by the adrenal glands not making enough of certain hormones. Primary adrenal insufficiency, also known as Addison's disease, is one form. Your adrenal glands are located [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - April 22, 2019 Category: Databases & Libraries Source Type: news

Adrenal insufficiency medical identification inadequate
According to a study, published inClinical Endocrinology, the majority of medical identification jewellery for patients with adrenal insufficiency does not have adequate information on how to treat adrenal crisis.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - April 16, 2019 Category: Endocrinology Source Type: news

Hydrocortisone muco-adhesive buccal tablets
should not be used off-label for treating adrenal insufficiency in children due to serious risks. There is a risk of insufficient cortisol absorption and li (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - December 19, 2018 Category: Drugs & Pharmacology Source Type: news

Mortality Data From the EU-AIR Mortality Data From the EU-AIR
What can data from the EU-AIR tell us about the characteristics of patients with adrenal insufficiency who have died?Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 27, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Adrenal Emergencies in Patients With Adrenal Insufficiency Adrenal Emergencies in Patients With Adrenal Insufficiency
A new study evaluates the management of emergency situations in patients with chronic adrenal insufficiency.Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - August 20, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Medical News Today: What is dexamethasone?
Dexamethasone oral tablet is a prescription medication used to treat conditions such as inflammation, allergic reactions, ulcerative colitis, and adrenal insufficiency. It's available as a generic drug and as the brand-name drugs DexPak and Decadron. Learn about side effects, warnings, dosage, and more. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - July 10, 2018 Category: Consumer Health News Tags: Pharmacy / Pharmacist Source Type: news

Inefficient management of emergency adrenal insufficiency
According to a German study, published inClinical Endocrinology, adrenal insufficiency patients experience highly variable waiting times for glucocorticoid treatment in emergency situations.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - April 23, 2018 Category: Endocrinology Source Type: news

What Causes Hyponatremia?
Discussion Normal kidneys regulate water balance to maintain a plasma osmolality of 275-290 mOsm/kg normally. Thirst and arginine vasopressin or antidiuretic hormone (ADH) are the primary regulators of plasma osmolality. ADH is made in the hypothalamus and released by the posterior pituitary gland. ADH acts on the kidney’s distal collecting duct to increase water reabsorption. ADH is appropriately released in hypovolemic states, such as dehydration caused by gastroenteritis. ADH has an ~10 minute half-life and therefore can respond to rapid changes in volume status. Sodium balance is regulated by aldosterone (as part...
Source: PediatricEducation.org - April 23, 2018 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Timing Cortisol Therapy Could Improve Adrenal Insufficiency Timing Cortisol Therapy Could Improve Adrenal Insufficiency
Giving cortisol replacement therapy in a pattern that mimics normal rhythms of human secretion could result in better sleep quality and cognitive function compared with standard dosing, say UK researchers. (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 19, 2018 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Timing of cortisol replacement therapy affects cognitive performance
According to a trial, published inPNAS, timing cortisol replacement therapy to more closely match the usual ultradian rhythm can improve cognitive function in patients with adrenal insufficiency.Medical Xpress (Source: Society for Endocrinology)
Source: Society for Endocrinology - April 12, 2018 Category: Endocrinology Source Type: news

Adrenal Insufficiency: Glucocorticoid Timing and Adverse Effects Adrenal Insufficiency: Glucocorticoid Timing and Adverse Effects
In patients with adrenal insufficiency, a once-daily, modified-release glucocorticoid regimen may reduce the recurrent infections and metabolic effects that can occur with multiple daily doses, researchers in Italy say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 28, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

New drugs approved for rare paediatric disorders
The EU has given approval for the use of new treatments in treating two rare paediatric endocrine disorders, primary adrenal insufficiency and X-linked hypophosphatemia.Medscape (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 20, 2017 Category: Endocrinology Source Type: news

EU Gives Okay to Two Drugs for Rare Pediatric Endocrine Disorders EU Gives Okay to Two Drugs for Rare Pediatric Endocrine Disorders
Pediatric primary adrenal insufficiency and X-linked hypophosphatemia are rare and debilitating conditions for which current treatments are limited.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - December 18, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news

Once a day glucocorticoid therapy improves health in adrenal insufficiency
According to an Italian study, published in theLancet Diabetes& Endocrinology, adrenal insufficiency patients treated once a day with hydrocortisone have improved immune and metabolic function compared with those on conventional therapy.Healio (Source: Society for Endocrinology)
Source: Society for Endocrinology - December 15, 2017 Category: Endocrinology Source Type: news

Central adrenal insufficiency following traumatic brain injury: a missed diagnosis in the critically injured - Fan E, Skippen PW, Sargent MA, Cochrane DD, Chanoine JP.
BACKGROUND: High-dose steroid administration is no longer recommended in the treatment of acute traumatic brain injury (TBI) as it failed to prove beneficial in improving patients' outcome. However, a masked benefit of steroid administration in TBI managem... (Source: SafetyLit)
Source: SafetyLit - July 24, 2017 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

The Medical Emergency Of Otto Warmbier
All that the doctors who treated Cincinnati, Ohio resident Otto Warmbier knew is what they had seen or maybe read in the news. They knew he had just been released on June 13 from imprisonment in North Korea where he had been held by for more than 17 months. He had been sentenced in March 2016 to 15 years of hard labor for allegedly removing a propaganda poster from a wall at a Pyongyang hotel where he had been staying. The University of Virginia honors student had been visiting the authoritarian state during a five-day trip with a group called Young Pioneer Tours, which is a group out of China – an important note. Ot...
Source: Healthy Living - The Huffington Post - June 22, 2017 Category: Consumer Health News Source Type: news

Prednisolone May Raise Cholesterol in Adrenal Insufficiency Prednisolone May Raise Cholesterol in Adrenal Insufficiency
The findings point to hydrocortisone as first-line treatment, but it is exceptionally expensive compared with prednisolone, at least in some countries, so studying lower doses of prednisolone may be worthwhile.Medscape Medical News (Source: Medscape Diabetes Headlines)
Source: Medscape Diabetes Headlines - April 3, 2017 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Salivary Cortisol and Cortisone in Adrenal Insufficiency Salivary Cortisol and Cortisone in Adrenal Insufficiency
Find out more about the diagnostic roles of salivary cortisol and cortisone levels in adrenal insufficiency.Journal of the Endocrine Society (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 24, 2017 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news

Your NEJM Group Today: New Resident Coaching Model, Hydrocortisone Dosing for Adrenal Insufficiency, Rocky Mountain IM Opportunity (FREE)
By the Editors NEJM Group offers so many valuable resources for practicing clinicians. Here's what we chose for you today:NEJM Knowledge+ Blog: A new … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - November 3, 2016 Category: Primary Care Source Type: news

Diurnal reports positive headline data from pivotal Phase III trial of Infacort to treat paediatric AI
UK-based pharmaceutical company Diurnal has reported positive headline data from its pivotal study of Infacort in Europe to treat paediatric adrenal insufficiency (AI). (Source: Drug Development Technology)
Source: Drug Development Technology - July 11, 2016 Category: Pharmaceuticals Source Type: news

Glucocorticoid Therapy for Adrenal InsufficiencyGlucocorticoid Therapy for Adrenal Insufficiency
How do patients with adrenal insufficiency feel about glucocorticoid therapy -- and how common is the problem of non-adherence? Clinical Endocrinology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 7, 2016 Category: Consumer Health News Tags: Diabetes & Endocrinology Journal Article Source Type: news