Are Oral Pain and Otalgia Predictive of Perineural Invasion in Squamous Cell Carcinoma of the Oral Tongue?

Squamous cell carcinoma of the oral tongue (SCCOT) has been reported as the most common cancer found in the oral cavity.1 Tongue cancer is often associated with pain and perineural invasion, which is typically defined by tumor cells invading perineural tissues, tracking along nerves, and/or surrounding at least one-third the circumference of nerves.2 The purpose of this study was to determine the association between tongue pain and otalgia and the microscopic identification of perineural invasion in patients with squamous cell carcinoma of the tongue.
Source: Journal of Oral and Maxillofacial Surgery - Category: ENT & OMF Authors: Source Type: research