Vorinostat Combined With Isotretinoin and Chemotherapy in Treating Younger Patients With Embryonal Tumors of the Central Nervous System

Conditions:   Untreated Childhood Medulloblastoma;   Untreated Childhood Supratentorial Primitive Neuroectodermal TumorInterventions:   Drug: Vorinostat;   Drug: Isotretinoin;   Drug: Vincristine Sulfate;   Drug: Cisplatin;   Drug: Cyclophosphamide;   Drug: Thiotepa;   Procedure: Peripheral Blood Stem Cell Transplantation;   Radiation: 3-Dimensional Conformal Radiation Therapy;   Other: Laboratory Biomarker AnalysisSponsor:   National Cancer Institute (NCI)Active, not recruiting - verified December 2014
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials