New Acne Guidelines Recommend Topical Combinations, Judicious Use of Antibiotics
(MedPage Today) -- Antibiotics, benzoyl peroxide, topical retinoids, and oral isotretinoin received strong recommendations for acne treatment from a panel of experts who drafted an update to the American Academy of Dermatology (AAD) clinical guidelines... (Source: MedPage Today Dermatology)
Source: MedPage Today Dermatology - February 15, 2024 Category: Dermatology Source Type: news

Pregnancies With Isotretinoin Exposure Rise Sharply Pregnancies With Isotretinoin Exposure Rise Sharply
The absolute annual number was low but doubled over a 15-year period, despite a longstanding prevention program.Medscape News UK (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - January 30, 2024 Category: Dermatology Tags: Dermatology Source Type: news

2004 to 2019 Saw Increase in Isotretinoin Use in Girls, Women
THURSDAY, Jan. 25, 2024 -- From 2004 to 2019, there was an increase in isotretinoin use among girls and women of childbearing age in Germany, according to a study published online Jan. 25 in PLOS Medicine.Jonas Reinold, from the Leibniz Institute... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - January 25, 2024 Category: Pharmaceuticals Source Type: news

FDA Mandates Changes to iPLEDGE Program for Isotretinoin FDA Mandates Changes to iPLEDGE Program for Isotretinoin
Isotretinoin manufacturers have 6 months to make five changes to existing iPLEDGE Risk Evaluation and Mitigation Strategy (REMS) requirements for isotretinoin.MDedge News (Source: Medscape Nurses Headlines)
Source: Medscape Nurses Headlines - December 6, 2023 Category: Nursing Tags: Dermatology Source Type: news

No Increased Suicide Risk Observed for Isotretinoin Users
MONDAY, Dec. 4, 2023 -- Isotretinoin users do not have an increased risk for suicide or psychiatric disorders and may have a lower risk for suicide attempts, according to a review published online Nov. 29 in JAMA Dermatology.Nicole Kye Wen Tan,... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - December 4, 2023 Category: Pharmaceuticals Source Type: news

Meta-Analysis: Suicide Risk Not Increased With Isotretinoin Meta-Analysis: Suicide Risk Not Increased With Isotretinoin
In fact, those treated with the drug for severe acne may have a lower risk for suicide attempts 2-4 years after treatment, according to the study authors.MDedge News (Source: Medscape Internal Medicine Headlines)
Source: Medscape Internal Medicine Headlines - December 1, 2023 Category: Internal Medicine Tags: Dermatology News Source Type: news

Risk of suicide and psychiatric disorders among isotretinoin users: a meta-analysis - Tan NKW, Tang A, MacAlevey NCYL, Tan BKJ, Oon HH.
IMPORTANCE: Isotretinoin is hypothesized to contribute to the development of psychiatric disorders, but the epidemiological association and risk factors associated with psychiatric disorders among isotretinoin users remain unclear. OBJECTIVE: To cl... (Source: SafetyLit)
Source: SafetyLit - December 1, 2023 Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

No Heightened Risk of Suicide, Psychiatric Conditions With Acne Drug
(MedPage Today) -- Use of the acne medication isotretinoin (Accutane) was not associated with an increased risk of suicide or psychiatric conditions in a meta-analysis of 24 observational studies. The 1-year pooled absolute risk of completed suicide... (Source: MedPage Today Psychiatry)
Source: MedPage Today Psychiatry - December 1, 2023 Category: Psychiatry Source Type: news

Should the acne drug that 'cost Annabel Wright and Jon Medland their lives' be banned for under-18s?
Isotretinoin - brand name Roaccutane - is a pill first licensed in the UK for the treatment of severe acne in 1983 and has since been taken by hundreds of thousands of patients. (Source: the Mail online | Health)
Source: the Mail online | Health - July 31, 2023 Category: Consumer Health News Source Type: news

Review: Oral Isotretinoin Is the Best Treatment for Acne
THURSDAY, July 27, 2023 -- The most effective treatment for acne is oral isotretinoin, according to a review published in the July/August issue of the Annals of Family Medicine. Chung-Yen Huang, M.D., from the National Taiwan University Hospital in... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 27, 2023 Category: Pharmaceuticals Source Type: news

Frustrations With Isotretinoin REMS Evident at FDA Meeting Frustrations With Isotretinoin REMS Evident at FDA Meeting
The FDA advisory panel meeting was held to address proposed changes to the iPLEDGE REMS to minimize burden on patients, prescribers, and pharmacies while maintaining safe use of isotretinoin.MDedge News (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - April 1, 2023 Category: Dermatology Tags: Dermatology News Source Type: news

FDA Panel Votes to Modify Isotretinoin iPLEDGE REMS FDA Panel Votes to Modify Isotretinoin iPLEDGE REMS
Advisory committee members voted to recommend changing the 19-day lockout for the drug for severe, nodular acne and the monthly attestation requirement for counseling people who cannot get pregnant.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - March 29, 2023 Category: Consumer Health News Tags: Dermatology News Alert Source Type: news

Do Away With 'Lockout' Period in iPLEDGE, FDA Advisors Urge
(MedPage Today) -- An FDA advisory committee on Wednesday voted 17-4 (with one abstention) to recommend removing a "lockout period" from a risk evaluation and mitigation strategy (REMS) for isotretinoin prescribing that requires patients to wait... (Source: MedPage Today OB/GYN)
Source: MedPage Today OB/GYN - March 29, 2023 Category: OBGYN Source Type: news

FDA Advisory Panels Consider Easing Isotretinoin Requirements FDA Advisory Panels Consider Easing Isotretinoin Requirements
The 19-day lockout, home pregnancy tests, and attestation intervals for counseling people who cannot get pregnant were among the hot topics on the first day of a 2-day meeting.Medscape Medical News (Source: Medscape Dermatology Headlines)
Source: Medscape Dermatology Headlines - March 29, 2023 Category: Dermatology Tags: Dermatology News Source Type: news

Isotretinoin REMS Still Needed, But Its Burden Could Be Reduced, FDA Staff Says
(MedPage Today) -- A risk evaluation and mitigation strategy (REMS) for the use of isotretinoin to treat severe acne is still very much needed, but there are ways to lighten its burden on patients and providers, according to FDA staff. For example... (Source: MedPage Today Public Health)
Source: MedPage Today Public Health - March 27, 2023 Category: American Health Source Type: news