Putative stemness markers octamer-binding transcription factor 4, sex-determining region Y-box 2, and NANOG in non-small cell lung carcinoma: A clinicopathological association

Conclusion: The expression and prognostic significance of CSC markers obviously vary depending on histological NSCLC subtype. Importantly, our findings suggest that OCT4, SOX2, and NANOG network together may be promising for ongoing targeted therapies in specific NSCLC subgroups.

Source: Journal of Cancer Research and Therapeutics - September 13, 2020 Category: Cancer & Oncology Authors: Vinal A Upadhyay Kanisha A Shah Dimple P Makwana Apexa P Raval Franky Dhaval Shah Rakesh M Rawal Source Type: research