Autophagy-related gene expression classification defines three molecular subtypes with distinct clinical and microenvironment cell infiltration characteristics in colon cancer.

CONCLUSIONS: This study may help understand the molecular characterization of autophagy-related subtypes. We demonstrated the autophagy genes in colon cancer could drive the heterogeneity of TME immune cell infiltration. Our study represented a step toward personalized immunotherapy in colon cancer. PMID: 32769067 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32769067?dopt=Abstract

Source: International Immunopharmacology - August 4, 2020 Category: Allergy & Immunology Authors: Zhu S, Wu Q, Zhang B, Wei H, Li B, Shi W, Fang M, Zhu S, Wang L, Lang Zhou Y, Dong Y Tags: Int Immunopharmacol Source Type: research