Big Small Cell Dilemma

A 49-year-old male with a history of locally advanced small cell prostate cancer presents with new-onset medically refractory constipation prompting concerns of impending bowel obstruction. Five months earlier, the patient had been diagnosised with stage IVA (T4N1M0) high-grade neuroendocrine carcinoma of the prostate during a workup for recurrent urinary tract infections, hydronephrosis, and sepsis. Palliative bilateral percutaneous nephrostomy tubes were placed. Staging with positron emission tomography/computed tomography (PET/CT) revealed a 9.7 × 12.0 × 13.0 cm heterogeneously enhancing prostatic mass involving the seminal vesicles, bladder and rectal walls, and right ureter, as well as extensive bulky bilateral pelvic lymphadenopathy (Fig. 1).
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Tags: Gray Zone Source Type: research