Acute paraparesis in HIV-infected patient after initiation of highly active antiretroviral therapy

We report a case of transverse myelitis in a recently diagnosed HIV patient who was otherwise asymptomatic initially and developed paraparesis after 1  month of initiation of antiretroviral therapy. After ruling out opportunistic infections and other causes of compressive and non-compressive myelopathy, development of transverse myelitis was attributed to immune reconstitution inflammatory syndrome in view of baseline low CD4 count and their impr ovement after HAART initiation. Prompt treatment with corticosteroids successfully reversed the symptoms.
Source: Journal of NeuroVirology - Category: Neurology Source Type: research