Cancers, Vol. 12, Pages 1292: Rho GTPases in Gynecologic Cancers: In-Depth Analysis toward the Paradigm Change from Reactive to Predictive, Preventive, and Personalized Medical Approach Benefiting the Patient and Healthcare

This article provides an in-depth overview on the role of Rho GTPases in gynecological cancers, highlights relevant signaling pathways and pathomechanisms, and sheds light on their involvement in tumor progression, metastatic spread, and radio/chemo resistance. In addition, insights into a spectrum of novel biomarkers and innovative approaches based on the paradigm shift from reactive to predictive, preventive, and personalized medicine are provided.

Source: Cancers - May 19, 2020 Category: Cancer & Oncology Authors: Pavol Zubor Zuzana Dankova Zuzana Kolkova Veronika Holubekova Dusan Brany Sandra Mersakova Marek Samec Alena Liskova Lenka Koklesova Peter Kubatka Jan Bujnak Karol Kajo Milos Mlyncek Frank A. Giordano Olga Golubnitschaja Tags: Review Source Type: research