Pediatric Lung Transplantation: Dynamics of the Microbiome and Bronchiolitis Obliterans in Cystic Fibrosis

Compositional changes in the microbiome are associated with the development of bronchiolitis obliterans (BO) after lung transplantation (LTx) in adults with cystic fibrosis (CF). The association between the lower airway bacterial community and BO after LTx in children with CF remains largely unexplored and is possibly influenced by frequent antibiotic therapy.

Source: The Journal of Heart and Lung Transplantation - May 12, 2020 Category: Transplant Surgery Authors: Ahmed A. Metwally, Christian Ascoli, Benjamin Turturice, Asha Rani, Ravi Ranjan, Yang Chen, Cody Schott, Albert Faro, Thomas W. Ferkol, Patricia W. Finn, David L. Perkins Source Type: research