Renin angiotensin system blockage by losartan neutralize hypercholesterolemia-induced inflammatory and oxidative injuries.

Conclusion: This study confirmed the pathological enrollment of renin-angiotensin system in hypercholesterolemia-associated metabolic alterations. LT had a significant cardiac, hepatic, and renal protective role against these impairments through down-regulation of oxidative damage, inflammation and necrosis. PMID: 32396454 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32396454?dopt=Abstract

Source: Redox Report : communications in free radical research - May 13, 2020 Category: Biochemistry Authors: AlSaad AMS, Alasmari F, Abuohashish HM, Mohany M, Ahmed MM, Al-Rejaie SS Tags: Redox Rep Source Type: research