Controlled Release of Oxycodone as an Opioid Titration for Cancer Pain Relief: A Retrospective Study.

Controlled Release of Oxycodone as an Opioid Titration for Cancer Pain Relief: A Retrospective Study. Med Sci Monit. 2020 Mar 18;26:e920598 Authors: Zhao S, Xu C, Lin R Abstract BACKGROUND In 2014, a Chinese expert consensus was proposed regarding a titration protocol with controlled-release (CR) oxycodone as a background dose for relieving the moderate to severe cancer pain. This work aimed to summarize its efficacy and safety in our hospital. MATERIAL AND METHODS The Good Pain Management (GPM) protocol comprises a CR morphine or oxycodone given every 12-hours as a background dose and an immediate-release (IR) opioid as a rescue dose. Cancer patients with moderate to severe cancer pain were treated with this protocol, and the successful titration (numerical rating scale [NRS] ≤3 within 3 days) rate was analyzed. SPSS was used for statistical analysis. Differences of variables between opioid intolerant patients and opioid tolerant patients were analyzed using the Mann-Whitney U test. The chi square test was used for comparison of frequencies in different groups. A P-value. PMID: 32225127 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research

Related Links:

CONCLUSION: Radiological imaging is essential for the management of patients affected by lung cancer. PMID: 32445458 [PubMed - as supplied by publisher]
Source: Current Radiopharmaceuticals - Category: Radiology Tags: Curr Radiopharm Source Type: research
Source: Patient Preference and Adherence - Category: International Medicine & Public Health Tags: Patient Preference and Adherence Source Type: research
Diabetic neuropathy has a major impact on morbidity and mortality. However, the diagnosis and management of diabetic neuropathy is South ‐East Asia is limited. Clear guidance is required to diagnose and manage patients with diabetic and other neuropathies. AbstractBurning and stabbing pain in the feet and lower limbs can have a significant impact on the activities of daily living, including walking, climbing stairs and sleeping. Peripheral neuropathy in particular is often misdiagnosed or underdiagnosed because of a lack of awareness amongst both patients and physicians. Furthermore, crude screening tools, such as the 10...
Source: Journal of Diabetes Investigation - Category: Endocrinology Authors: Tags: Review Article Source Type: research
Childhood cancer care is delivered by interprofessional healthcare teams however little is known about how parents perceive overall team-delivered care (TDC).
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Tags: Brief Report Source Type: research
No abstract available
Source: Oncology Times - Category: Cancer & Oncology Tags: News Source Type: research
We report a case morphine toxicity in an elderly patient of lung cancer with concomitant presence of chronic obstructive pulmonary disease (COPD) and recent onset renal impairment. Opioid analgesic overdose is a lethal but at the same time, a preventable and treatable condition. We managed the case using naloxone infusion. However, we emphasize early anticipation and recognition of predisposing factors followed by timely intervention to manage this life-threatening condition. PMID: 32421843 [PubMed - in process]
Source: Journal of Opioid Management - Category: Addiction Tags: J Opioid Manag Source Type: research
Multiple randomized clinical trials have demonstrated that palliative care improves the quality of life of individuals with serious medical illness. Research also suggests that in patients with advanced cancer, palliative care ’s focus on symptom management, coping with illness, goals of care, and treatment decisions may be associated with improved patient quality of life in part by increasing patients’ use of active (versus passive) and approach-oriented (versus avoidant) coping strategies. However, without a framewo rk outlining the process that individuals with serious medical illness and their loved ones un...
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Tags: Special Article Source Type: research
Suzuki Ian Bellayr Pamela Leland Bharat H. Joshi Raj K. Puri Perineural invasion (PNI) is one of the major pathological characteristics of pancreatic ductal adeno-carcinoma (PDAC), which is mediated by invading cancer cells into nerve cells. Herein, we identify the overexpression of Interleukin-13 Receptor alpha2 (IL-13Rα2) in the PNI from 236 PDAC samples by studying its expression at the protein levels by immunohistochemistry (IHC) and the RNA level by in situ hybridization (ISH). We observe that ≥75% samples overexpressed IL-13Rα2 by IHC and ISH in grade 2 and 3 tumors, while &...
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
This study aimed to analyze the available evidence and to describe the benefits of the new technologies in the treatment of pain, anxiety, and depression in children and adolescents with cancer. A systematic search using six electronic databases was conducted to identify studies using technological interventions with a focus on pain, anxiety, and depression that were published from 2008 to 2018 including oncology patients from 0–18 years old. Out of the 1261 studies that were identified, five studies met the inclusion criteria for this systematic review. Robots were used in two studies, providing amusement and so...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Review Source Type: research
Chronic pain is physiologically distinct from long-lasting acute pain. In some cases, however, poorly managed acute pain can develop into a chronic pain condition.In addition to the direct physical suffering that patients experience, the biopsychosocial nature of chronic pain affects their social lives, ability to work, and psychological well-being. The resulting economic burden of chronic pain is estimated to cost the United States over half a trillion dollars annually —more than diabetes, heart disease, and cancer combined.In this three-part series, doctors at the Pain Management Center of Stanford University exami...
Source: Psychology of Pain - Category: Anesthesiology Source Type: blogs
More News: Biomedical Science | Cancer | Cancer & Oncology | China Health | Hospitals | Morphine | Oxycodone | OxyContin | Pain | Pain Management | Research | Science | Statistics | Study