Extended-spectrum beta-lactamases producing extensively drug-resistant Salmonella Typhi in Punjab, Pakistan

Conclusions: The higher prevalence of ESBL producingSalmonella typhi clinical strains raises the concern about transmission prevention and infection management in the community as well as clinical settings. Moreover, the study highlights the problem concerning the declining antibiotic arsenal for the therapeutic management of typhoid fever and the emergence and spread of XDR strains in Pakistan.
Source: The Journal of Infection in Developing Countries - Category: Infectious Diseases Source Type: research

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CONCLUSION: Prevalence of antibiotic use was high not only versus other hospitals in the region but globally including Africa, coupled with significant evidence of sub-optimal prescribing. Swift action is needed to improve future prescribing to reduce AMR. One or two areas should initially be targeted for quality improvement including development of local guidelines, documentation of antibiotic indications and/or stop/review dates. PMID: 33034234 [PubMed - as supplied by publisher]
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research
Authors: Reissier S, Cattoir V Abstract INTRODUCTION: Streptogramins (pristinamycin and quinupristin-dalfopristin) can be interesting options for the treatment of infections due to Gram-positive cocci, especially multidrug-resistant isolates. AREAS COVERED: This review provides an updated overview on structural and activity characteristics, mechanisms of action and resistance, pharmacokinetic/pharmacodynamic and clinical use of streptogramins. EXPERT OPINION: The streptogramin antibiotics act by inhibition of the bacterial protein synthesis. They are composed of two chemically distinct compounds, namely typ...
Source: Expert Review of Anti-Infective Therapy - Category: Infectious Diseases Tags: Expert Rev Anti Infect Ther Source Type: research
Publication date: Available online 9 October 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Manuel Jorge Rial, Marcela Valverde, Victoria del Pozo, Francisco Javier González-Barcala, Carlos Martínez-Rivera, Xavier Muñoz, José María Olaguibel, Vicente Plaza, Elena Curto, Santiago Quirce, Pilar Barranco, Javier Domínguez-Ortega, Joaquin Mullol, César Picado, Antonio Valero, Irina Bobolea, Ebymar Arismendi, Paula Ribó, Joaquín Sastre
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Trump plans in-person rally on Monday as next presidential debate cancelled; Europe records 100,000 daily cases for first time; Canada at ‘tipping point’. Follow latest updatesEurope: Spain declares emergency in Madrid as Berlin emerges as hotspotUK workers to get two-thirds of wages if firms told to shutAustralia: Is Victoria ready to come out of lockdown?US presidential debate cancelled – live updatesSee all our coronavirus coverage5.42amBSTMy colleagueLuke Henriques-Gomes has this story giving you a summary of the main Covid-19 stories from Australia.A main point of the day has beenVictoria ’s pr...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak Infectious diseases Science World news France Trump administration Donald Trump Source Type: news
In this digital age the impact of media can be observed in all walks of life. All media users are being influenced by one or another type of media, however the amount of effect and time may vary. One cannot deny the fact that the images that are being show...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Adolescents Source Type: news
Publication date: Available online 9 October 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Elma L. Leite, Wydemberg J. Araújo, Tatiana R. Vieira, Karoline S. Zenato, Priscylla C. Vasconcelos, Samuel Cibulski, Patricia E.N. Givisiez, Marisa R.I. Cardoso, Celso J.B. Oliveira
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Publication date: Available online 8 October 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): E.L. Looman, P. van Tienen, D.Y.K. Ng, S. Baig, A. Fait, S. Overballe-Petersen, P.S. Andersen, M. Stegger
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
ConclusionThe meta-analysis suggested the substantial role ofVEGF polymorphism rs3025039 as a possible biomarker for the assessment of DR risk. However, genome-wide association study (GWAS) is required in future to elucidate the multi-SNP effect of these polymorphisms inVEGF gene.
Source: International Journal of Diabetes in Developing Countries - Category: Endocrinology Source Type: research
WHO emergencies chiefwarns ‘there are no new answers’ as cases surge globally. This blog has now closed. Follow our latest blog belowCoronavirus – latest updates12.58amBSTWe are closing this live blog now, but you can stay up to date on all the latest news, including a press conference from Victoria at 11am, hosted by Daniel Andrews, on our new blog below:Related:Coronavirus live news: France sets daily record 20,000 cases; Australian state of Victoria reports 14 new infections12.43amBSTI ’ve just got some clarification on the “positive test result” reported for Goodna, near Ipswich, wes...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Coronavirus outbreak World news UK news US news Australia news Science Infectious diseases Source Type: news
The coronavirus outbreak has indelibly imprinted itself on life in Los Angeles — down to the composition of trash washing up on its beaches.
Source: L.A. Times - Health - Category: Consumer Health News Authors: Source Type: news
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