Cancers, Vol. 12, Pages 611: Age-Dependent Presentation and Clinical Course of 1465 Patients Aged 0 to Less than 18 Years with Ovarian or Testicular Germ Cell Tumors; Data of the MAKEI 96 Protocol Revisited in the Light of Prenatal Germ Cell Biology

Conclusions: The different pathogenesis and histogenesis of gonadal GCT reflects sex- and age-specific patterns that define clinically relevant risk groups. Therefore, gender and age should be considered in further research on the biology and clinical practice of pediatric gonadal GCT.

Source: Cancers - March 5, 2020 Category: Cancer & Oncology Authors: Gabriele Calaminus Dominik T. Schneider Dietrich von Schweinitz Heribert J ürgens Nacera Infed Stefan Sch önberger Thomas A. Olson Peter Albers Christian Vokuhl Raimund Stein Leendert Looijenga Jalid Sehouli Martin Metzelder Alexander Claviez Michael Dw Tags: Article Source Type: research