TRIM34 attenuates colon inflammation and tumorigenesis by sustaining barrier integrity.

This study indicates that TRIM34 expression in GCs plays an essential role in generating the inner mucus layer and preventing excessive colon inflammation and tumorigenesis.
PMID: 32094504 [PubMed - as supplied by publisher]

Source: Cellular and Molecular Immunology - February 23, 2020 Category: Molecular Biology Authors: Lian Q, Yan S, Yin Q, Yan C, Zheng W, Gu W, Zhao X, Fan W, Li X, Ma L, Ling Z, Zhang Y, Liu J, Li J, Sun B Tags: Cell Mol Immunol Source Type: research