Brain abnormalities on neuroimaging in Children with Congenital Zika Syndrome in Salvador, Brazil and its possible implications on neuropsychological development.

Brain abnormalities on neuroimaging in Children with Congenital Zika Syndrome in Salvador, Brazil and its possible implications on neuropsychological development. Int J Dev Neurosci. 2020 Feb 17;: Authors: Sanders Pereira Pinto P, de Almeida TM, Monteiro L, da Silva Souza MM, Dos Santos GAA, Cardoso CW, Dos Santos LM, Ribeiro GS, Dos Santos DN Abstract OBJECTIVE: to characterize the spectrum of brain damages presented in children affected by Congenital Zika Syndrome (CZS), verify the existence of a co-occurrence pattern of these damages and discuss possible implications for the neuropsychological development. METHODS: descriptive, quantitative, individualized and cross-sectional study using secondary sources. We selected 136 children with CZS from the database of the Center of Strategic Information on Health Vigilance of the Municipal Office of Salvador, Brazil. We conducted descriptive and multiple correspondence analyses. RESULTS: Among the set of analyzed variables, microcephaly (51.5%), ventriculomegaly (57.4%) and brain calcifications (77.2%) were identified as the most frequent. The multiple correspondence analysis showed that the combination of these three variables (32.4%) was what better represented the spectrum of brain damages in the Central Nervous System. INTERPRETATION: Damage in the sensory-motor, cognitive and language development, as well as neurodevelopmental disorders, are described in the l...
Source: International Journal of Developmental Neuroscience - Category: Neuroscience Authors: Tags: Int J Dev Neurosci Source Type: research