Bacterial, viral, and fungal infection ‐related risk of Parkinson's disease: Meta‐analysis of cohort and case–control studies

Bacterial, viral, or overall infection was associated with increased Parkinson's disease risk.Helicobacter pylori, hepatitis C virus, Malassezia, and pneumoniae infection were positively associated with the risk of Parkinson's disease. However, infection of herpes virus, hepatitis B virus, pertussis, scarlet fever, mumps, chicken pox, influenza virus, measles, and German measles was not. AbstractAimsRecent studies showed that patients with various bacterial, viral, and fungal infections might be at increased risk of Parkinson's disease (PD). However, the risk of PD in patients with each specific infection varied. This meta ‐analysis estimated the association between various infections and PD risk.MethodsLiterature published from January 1965 to October 2019 in PubMed and EMBASE databases was searched. Data were extracted and pooled using random/fixed effects model. Sensitivity analysis and meta ‐regression were also performed to analyze the source of heterogeneity. Publication bias was estimated by the trim and fill.ResultsTwenty ‐three out of 6,609 studies were included.Helicobacter pylori (HP; pooled OR  = 1.653, 1.426–1.915,p 
Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL RESEARCH Source Type: research

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Authors: Feres M, Retamal-Valdes B, Faveri M, Duarte P, Shibli J, Soares GMS, Miranda T, Teles F, Goodson M, Hasturk H, Van Dyke T, Ehmke B, Eickholz P, Schlagenhauf U, Meyle J, Koch R, Kocher T, Hoffmann T, Kim TS, Kaner D, Figueiredo LC, Doyle H Abstract OBJECTIVE: The selection of proper outcome measures is a critical step in clinical research. Most randomized clinical trials (RCTs) assessing the effects of initial anti-infective periodontal therapies use surrogate outcomes as primary outcome variables, such as mean changes in probing depth (PD) or in clinical attachment. However, these parameters do not reflect...
Source: Journal of the International Academy of Periodontology - Category: Dentistry Tags: J Int Acad Periodontol Source Type: research
Context: In the midst of the current opioid epidemic, states have selected differing legislative routes implementing pathways to ensure access to clean needles and syringes. Objective: To determine whether states that implemented laws supporting syringe exchange programs (SEPs) had reductions in transmission rates of hepatitis B, hepatitis C, and HIV infection compared with states without such laws. Design and Setting: Utilizing a longitudinal panel design, we determined the legal status of SEPs in each state for years 1983-2016. Disease transmission rates for this period were estimated via a simple Poisson regress...
Source: Journal of Public Health Management and Practice - Category: Health Management Tags: Research Reports: Research Full Report Source Type: research
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Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
FDA is proposing to reclassify certain Hepatitis C (HCV) diagnostic tests from class III to II. Once finalized, tests of this type and use will go through FDA’s 510(k) pathway. Learn more: https://go.usa.gov/xvCuw  &https://go.usa.gov/xvCuH  pic.twitter.com/UXLETnMnJj
Source: Food and Drug Adminstration (FDA): CDRHNew - Category: Medical Devices Authors: Source Type: news
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Source: NYT Health - Category: Consumer Health News Authors: Tags: your-feed-science Seizures (Medical) Coronavirus (2019-nCoV) Fever Senses and Sensation Nerves and Nervous System Smell (Olfaction) Boca Raton (Fla) China Europe Germany France Wuhan (China) United States your-feed-health Source Type: news
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Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Source Type: news
Authors: Ventura CG, Roque FL, Sousa IQ, Lobo RD, Luders C Abstract INTRODUCTION: Chronic hemodialysis (HD) patients are considered to be at high risk for infection. Here, we describe the clinical outcomes of chronic HD patients with influenza A (H1N1) infection and the strategies adopted to control an outbreak of influenza A in a dialysis unit. METHODS: Among a total of 62 chronic HD patients, H1N1 infection was identified in 12 (19.4%). Of the 32 staff members, four (12.5%) were found to be infected with the H1N1 virus. Outcomes included symptoms at presentation, comorbidities, occurrence of hypoxemia, hospit...
Source: Jornal Brasileiro de Nefrologia - Category: Urology & Nephrology Tags: J Bras Nefrol Source Type: research
WEDNESDAY, April 1, 2020 -- Telephone-based cognitive behavioral therapy (T-CBT) seems to be an effective intervention for depression in Parkinson disease (PD), outperforming treatment-as-usual (TAU) on all depression, anxiety, and quality-of-life...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
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Source: FT.com - Drugs and Healthcare - Category: Pharmaceuticals Source Type: news
Today, the @US_FDA proposes to reclassify two types of hepatitis C virus (HCV) diagnostic tests from class III to II. If this reclassification is finalized, tests of this type and use may go through the FDA’s 510(k) pathway for clearance.
Source: Food and Drug Adminstration (FDA): CDRHNew - Category: Medical Devices Authors: Source Type: news
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