Iron-Induced Derangement in hepatic Δ-5 and Δ-6 Desaturation Capacity and Fatty Acid Profile Leading to Steatosis: Impact on Extrahepatic Tissues and Prevention by Antioxidant-Rich Extra Virgin Olive Oil

In conclusion, AR-EVOO supplementation prevents IRD-induced changes in parameters related to liver FA metabolism and steatosis, an effect that may have a significant impact in the treatment of iron-related pathologies or metabolic disorders such as non-alcoholic fatty liver disease.Graphical Abstract
Source: Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) - Category: Lipidology Source Type: research