Up to 43% of Antibiotic Prescriptions in the U.S. Are Unnecessary or Improperly Written, Analysis Finds

The World Health Organization earlier this year called antimicrobial resistance—pathogens’ ability to evade medical interventions—one of the 10 largest threats to global health. In the U.S. alone, according to a recent Centers for Disease Control and Prevention (CDC) report, 35,000 people die each year due to antibiotic-resistant infections. A new study published in the BMJ points to one major propagator of the problem: doctors are prescribing antibiotics when they shouldn’t. In fact, up to 43% of U.S. antibiotic prescriptions may be “inappropriate,” according to the research. Antibiotics either kill bacteria or keep them from multiplying. By definition, they work only against bacterial illnesses—and yet, research shows they’re often needlessly prescribed for viral illnesses like the flu and common colds. That’s not only a waste of resources; it may also contribute to antibiotic resistance, since bacteria get better and better at evading drugs each time they encounter them. The authors of the BMJ paper analyzed data from the National Ambulatory Medical Care Survey, which asks a representative sample of U.S. physicians to describe patients’ office visits during a specified period of time. The authors examined data from more than 28,000 medical visits that took place in 2015, which can be statistically extrapolated to represent almost 991 million visits nationwide. Antibiotics were prescribed during 13.2% of these vis...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Research Source Type: news

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CONCLUSIONS.: There is a great variability of mutations associated with resistance to anti-tuberculosis drugs that have been reported in Peru, and they are systematized in this report. These mutations must be taken into account for the development of diagnostic devices or selection of diagnostic tests to be applied in our country. PMID: 31967255 [PubMed - in process]
Source: Revista Peruana de Medicina de Experimental y Salud Publica - Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research
Authors: Lai G, Guo N, Jiang Y, Lai J, Li Y, Lai R Abstract OBJECTIVE: To assess whether the duration of one-lung ventilation (OLV) affects postoperative pulmonary complications after McKeown esophagectomy for esophageal cancer. METHODS: A retrospective analysis of data stored in a database for esophageal cancer was carried out to identify predictors of postoperative pulmonary complications in patients undergoing McKeown esophagectomy at Sun Yat-sen University Cancer Center between 2010 and 2012. RESULTS: Patients in the OLV ⩾150 minutes group had a higher incidence of postoperative pulmonary complication...
Source: Tumori - Category: Cancer & Oncology Tags: Tumori Source Type: research
Publication date: February 2020Source: The Lancet Global Health, Volume 8, Issue 2Author(s): Jeremy D Keenan, Ahmed M Arzika, Ramatou Maliki, Sanoussi Elh Adamou, Fatima Ibrahim, Mariama Kiemago, Nana Fatima Galo, Elodie Lebas, Catherine Cook, Benjamin Vanderschelden, Robin L Bailey, Sheila K West, Travis C Porco, Thomas M Lietman, Paul M Emerson, Jerusha Weaver, Sheila K West, Robin L Bailey, John Hart, Amza AbdouSummaryBackgroundThe Macrolides Oraux pour Réduire les Décès avec un Oeil sur la Résistance (MORDOR) trial found that biannual mass distribution of azithromycin to children younger tha...
Source: The Lancet Global Health - Category: International Medicine & Public Health Source Type: research
Have any of y'all thought about this? For example, if someone comes into the ED with flu like symptoms, in the middle of flu season, and is an otherwise young and healthy individuals, I see no utility in testing for the flu (I'm also not a fan of Tamiflu for non-high risk populations), so it's usually just r/o something like a pneumonia, reassurance, doctor's note, and OTC symptom control. But with these periodic outbreaks of things like SARS, MERS, this novel corona virus, or even failed... What's the ER doc's role in epidemiology?
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Emergency Medicine Source Type: forums
A pediatric healthcare worker in Michigan had tuberculosis and didn't know it while working in several locations over nine months, the state's health department said.ment said.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news
Scientists at Northwestern University in Illinois studied 166 indoor dust samples and found that bacteria living within them were able to share antibiotic resistant genes with each other.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
ConclusionAccording to the notable anti-inflammatory effect in vitro and its joint protective effects on a septic mouse model, SESLA might act as an adjuvant drug candidate for sepsis, even those caused by antibiotic-resistant bacteria, e.g., CRKP.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 22 January 2020Source: International Journal of PharmaceuticsAuthor(s): Sara García-Salinas, Michael Evangelopoulos, Enrique Gámez-Herrera, Manuel Arruebo, Silvia Irusta, Francesca Taraballi, Gracia Mendoza, Ennio TasciottiAbstractWound healing is a complex process that consists of three overlapping phases: inflammation, proliferation, and remodeling. A bacterial infection can increase inflammation and delay this process. Microorganisms are closely related to the innate immune system, such as macrophages and neutrophils, as they can start an inflammatory cascade. Essential o...
Source: International Journal of Pharmaceutics - Category: Drugs & Pharmacology Source Type: research
BOSTON (CBS) – The Centers for Disease Control has raised its travel notice for Wuhan, China to the highest level because of an outbreak of the coronavirus. The virus has already killed at least 17 people in China and more than 600 people are sick. Dr. Mallika Marshall says there are other coronaviruses, but this one is dangerous because it is new. Health officials are trying to figure out how contagious it is, and are trying to develop a vaccine against it, but it takes time. Symptoms are similar to a respiratory infection and include fever, runny nose and cough. It can progress quickly to a severe pneumonia-like ...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health Syndicated Local Coronavirus Dr. Mallika Marshall Source Type: news
This study is a randomized, patient-assessor blind, controlled, parallel, and multicenter clinical trial. A total of 375 participants diagnosed with the common cold were enrolled via four hospitals. The common cold patients will take a daily dose of Eunkyosan or Samsoeum or a placebo, three times a day for eight days. The primary outcome is the change in total Wisconsin Upper Respiratory Symptom Scale-21-Korean (WURSS-21-K) score between baseline and six days. The secondary outcome includes the visual analogue scale (VAS). Safety is evaluated and adverse events are assessed throughout the trial. Written informed consent wi...
Source: Integrative Medicine Research - Category: Complementary Medicine Source Type: research
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