Burden of comorbidities in patients with OSA and COPD-OSA overlap syndrome

Introduction: Obstructive sleep apnea (OSA) and chronic obstructive pulmonary (COPD), are usually accompanied by several comorbidities. Aim of the study was to assess the prevalence of comorbidities in OSA and COPD-OSA overlap syndrome (OS) patients and to explore differences between these two groups.Methods: Included were consecutive OS (n=163, 138 males, AHI>5/h and FEV1/FVC5/h and FEV1/FVC>0.7), matched in terms of gender, age, BMI, and smoking history, diagnosed with polysomnography and pulmonary function testing.Results: As mentioned, the two groups were matched in age (p=0.221), BMI (p=0.496) and neck circumference (p=0.922). No difference was observed in ESS values (p=0.988), AHI (p=0.346), ODI (p=0.668) and minimum sleep oxyhaemoglobin saturation (p=0.100). Compared to OSA patients, OS patients had lower average sleep oxyhaemoglobin (p=0.008), higher sleep time with oxygen saturation
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sleep and control of breathing Source Type: research

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