Anti-Inflammatory Peptides From Cardiac Progenitors Ameliorate Dysfunction After Myocardial Infarction [Heart Failure]

Conclusions
Soluble JAM-A secreted from cardiac progenitor cells reduces infiltration of neutrophils after myocardial infarction and ameliorates tissue damage through prevention of excess inflammation. Our finding may lead to a new therapy for cardiovascular disease by using the anti-inflammatory effect of JAM-A.

Source: JAHA:Journal of the American Heart Association - December 2, 2014 Category: Cardiology Authors: Liu, M.-L., Nagai, T., Tokunaga, M., Iwanaga, K., Matsuura, K., Takahashi, T., Kanda, M., Kondo, N., Naito, A. T., Komuro, I., Kobayashi, Y. Tags: Heart Failure Source Type: research