Degree centrality of key brain regions of attention networks in children with primary nocturnal enuresis: A resting-state functional magnetic resonance imaging study.

Degree centrality of key brain regions of attention networks in children with primary nocturnal enuresis: A resting-state functional magnetic resonance imaging study. Int J Dev Neurosci. 2019 Oct 12;: Authors: Jiang K, Yi Y, Ding L, Li H, Li Y, Yang M, Zheng A Abstract Primary nocturnal enuresis (PNE) is always associated with attention impairment, some of which even could develop to attention deficit hyperactivity disorder. The mechanism of attention impairment is not clear, especially lacking of objective indicators of neuroimaging. The aim of this study is to explore the possible functional imaging mechanism of impaired attention in PNE children. A total of 26 PNE children and 26 age-matched normal controls were recruited. Resting-state functional magnetic resonance imaging (rs-fMRI) was performed on these children. Degree centrality (DC) of key brain regions of DAN (lFEF, rFEF, lIFG, rIFG, lIPS, rIPS), VAN (TPJ, VFC) and DMN (PCC, aMPFC, lAG, rAG) were calculated and compared between PNE and normal children. And the correlations between DC values and attention behavioral results were measured. Compared with normal controls, PNE children exhibited lower DC value in the right frontal eye field (rFEF), left inferior parietal sulcus (lIPS), right inferior parietal sulcus (rIPS), temporal parietal junction (TPJ) and left angular gyrus (lAG). The correct number of continuous performance test (CPT) in the PNE group was significantly low...
Source: International Journal of Developmental Neuroscience - Category: Neuroscience Authors: Tags: Int J Dev Neurosci Source Type: research