Quantification of apparent axon density and orientation dispersion in the white matter of youth born with congenital heart disease

ConclusionLower apparent density of axonal packing, but not altered axonal orientation, is a key microstructural factor in the white matter abnormalities observed in youth born with CHD. These impairments in axonal packing may be an enduring consequence of early life brain injury and dysmaturation and may explain some of the long-term neuropsychological difficulties experienced by this at-risk group.
Source: NeuroImage - Category: Neuroscience Source Type: research