Salt restriction lowers blood pressure at rest and during exercise without altering peripheral hemodynamics in hypertensive individuals.

Salt restriction lowers blood pressure at rest and during exercise without altering peripheral hemodynamics in hypertensive individuals. Am J Physiol Heart Circ Physiol. 2019 Oct 04;: Authors: Ratchford SM, Broxterman RM, La Salle DT, Kwon OS, Hopkins PN, Richardson RS, Trinity JD Abstract Dietary salt restriction is a well-established approach to lower blood pressure and reduce cardiovascular disease risk in hypertensive individuals. However, little is currently known regarding the effects of salt restriction on central and peripheral hemodynamic responses to exercise in those with hypertension. Therefore, this study sought to determine the impact of salt restriction on the central and peripheral hemodynamic responses to static-intermittent handgrip (HG) and dynamic single-leg knee extension (KE) exercise in patients with hypertension. Twenty-two patients (14M / 8F, 51 ± 10y, 173 ± 11cm, 99 ± 23kg) forwent their antihypertensive medication use for at least 2 weeks prior to embarking on a 5-d liberal salt (LS: 200 mmol/d) diet followed by a 5-d restricted salt (RS: 10 mmol/d) diet. Patients were studied at rest and during static intermittent HG exercise at 15, 30, and 45 % of maximal voluntary contraction and KE exercise at 40, 60, and 80 % of maximum KE work rate. Salt restriction lowered resting systolic blood pressure (supine: -12 ± 3 mmHg, seated: -17 ± 2 mmHg) and diastolic blood pressure (supine: -3 ± 2 mmHg, seated: -5 Â...
Source: American Journal of Physiology. Heart and Circulatory Physiology - Category: Physiology Authors: Tags: Am J Physiol Heart Circ Physiol Source Type: research