Treatment of Growth Hormone Excess is Associated with Improvement in Abnormal Cardiac Phenotypes

Cardiovascular disease is the leading cause of mortality in patients with growth hormone (GH) hypersecretion, termed acromegaly. The traditional manifestation of GH excess is cardiac hypertrophy, but a dilated phenotype with clinical heart failure exists. Prior studies have suggested that treatment of GH excess may lead to an improvement in early stage dysfunction, but have shown no benefit in dilated cardiomyopathy or advanced disease.

Source: Journal of Cardiac Failure - July 31, 2019 Category: Cardiology Authors: Raghav R. Julakanti, Andrew N. Rosenbaum, Grace Lin Tags: 139 Source Type: research