Organophosphate pesticide metabolite concentrations in urine during pregnancy and offspring attention-deficit hyperactivity disorder and autistic traits.

CONCLUSIONS: In this study of maternal urinary DAP metabolite concentrations during pregnancy, we did not observe associations with ADHD and autistic traits in children. These are important null observations because of the relatively high background DAP concentrations across pregnancy, the relatively large sample size, and the 10-year follow-up of the offspring. Given the measurement error inherent in our OP pesticide exposure biomarkers, future studies using more urine samples are needed to accurately measure OP pesticide exposure over pregnancy in relation to ADHD and autistic traits.
PMID: 31369979 [PubMed - as supplied by publisher]

Source: Environment International - July 28, 2019 Category: Environmental Health Authors: van den Dries MA, Guxens M, Pronk A, Spaan S, El Marroun H, Jusko TA, Longnecker MP, Ferguson KK, Tiemeier H Tags: Environ Int Source Type: research