General Anesthesia Safety in Progressive Leukodystrophies: A Retrospective Study of Patients with Krabbe Disease and Metachromatic Leukodystrophy.
CONCLUSIONS: Although the complication rate for patients with Krabbe disease and metachromatic leukodystrophy is higher than the general population, most complications were mild and self-limiting. These results suggest that, in experienced hands, general anesthesia is well tolerated in most children. Findings show that the Neurodevelopment in Rare Disorders classification system is a better indicator for assessing complication risk in patients with Krabbe and metachromatic leukodystrophy than American Society of Anesthesiologists Physical Status.
PMID: 31359511 [PubMed - as supplied by publisher]
Source: Paediatric Anaesthesia - Category: Anesthesiology Authors: Bascou NA, Marcos MC, Beltran ML, Roosen-Marcos MC, Cladis FP, Poe MD, Escolar ML Tags: Paediatr Anaesth Source Type: research
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