Pleiotropic Effects of Statin in Therapy in Heart Failure: A Review.

Pleiotropic Effects of Statin in Therapy in Heart Failure: A Review.
Curr Vasc Pharmacol. 2014 Nov 27;
Authors: Correale M, Abruzzese S, A Greco C, Concilio M, Di Biase M, D Brunetti N
Abstract
Clinical trials demonstrated that statin therapy is associated with a significant reduction in cardiovascular morbidity and mortality when used for either primary or secondary prevention of cardiovascular events. Several studies have shown that statins, having an important effect in the prevention of acute coronary syndromes, are also able to prevent heart failure (HF) in patients with coronary artery disease. This review summarizes the experimental and clinical evidence regarding the role of statins in the management of HF.
PMID: 25440594 [PubMed - as supplied by publisher]

Source: Current Vascular Pharmacology - November 27, 2014 Category: Drugs & Pharmacology Authors: Correale M, Abruzzese S, A Greco C, Concilio M, Di Biase M, D Brunetti N Tags: Curr Vasc Pharmacol Source Type: research