Molecules, Vol. 24, Pages 2046: Phenolic Compounds from Five Ericaceae Species Leaves and Their Related Bioavailability and Health Benefits

Molecules, Vol. 24, Pages 2046: Phenolic Compounds from Five Ericaceae Species Leaves and Their Related Bioavailability and Health Benefits Molecules doi: 10.3390/molecules24112046 Authors: Bianca Eugenia Ștefănescu Katalin Szabo Andrei Mocan Gianina Crişan Some species of the Ericaceae family have been intensively studied because of the beneficial health impact, known since ancient times, of their chemical components. Since most studies focus on the effects of fruit consumption, this review aims to highlight the phenolic components present in the leaves. For this purpose, five species from Ericaceae family (bilberry—Vaccinium myrtillus L., lingonberry—V. vitis-idaea L., bog bilberry—V. uliginosum L., blueberry—V. corymbosum L. and bearberry—Arctostapylos uva-ursi L.) were considered, four of which can be found in spontaneous flora. The chemical composition of the leaves revealed three major phenolic compounds: chlorogenic acid, quercetin and arbutin. The health promoting functions of these compounds, such as antioxidant and anti-inflammatory properties that could have preventive effects for cardiovascular disease, neurodegenerative disorders, cancer, and obesity, have been exemplified by both in vitro and in vivo studies in this review. Furthermore, the importance of bioaccessibility and bioavailability of the phenolic compounds have been summarized. The findings highlight the fact that le...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research