T171. Implication of FOXP2 and DRD2 in the Associations Between Computerized Device Use and Psychiatric Disorders

Computerized device uses (CDU; e.g., playing computer games (CompGaming), mobile phone use (minutes/week for the last three months (PhoneUse) and total usage years), hands-free/speakerphone device use). Epidemiological associations between CDUs and psychiatric disorders are frequently reported; the biological mechanisms underlying these observations remain unknown. We investigated genetic overlap and causality between CDUs and psychiatric disorders (attention deficit hyperactivity disorder (ADHD), schizophrenia (SCZ), autism spectrum disorder, major depressive disorder, alcohol dependence, bipolar disorder, anorexia nervosa, and posttraumatic stress disorder) using LD score regression (LDSC) and Mendelian randomization (MR).
Source: Biological Psychiatry - Category: Psychiatry Authors: Source Type: research