Chemotherapy acutely impairs neurovascular and hemodynamic responses in women with breast cancer.

CONCLUSION: Adjuvant CHT with DX and CY in patients treated for breast cancer increases sympathetic nerve activity and circulating EMPs levels, which may synergistically contribute to reduce muscle vascular conductance and elevated systemic BP. These responses may be early signs of CHT-induced cardiovascular alterations and may represent potential targets for preventive interventions.
PMID: 31002284 [PubMed - as supplied by publisher]

Source: American Journal of Physiology. Heart and Circulatory Physiology - April 18, 2019 Category: Physiology Authors: Sales ARK, Negrao M, Testa L, Ferreira-Santos L, Groehs RRV, Carvalho B, Toschi-Dias E, Rocha NG, Laurindo F, Debbas V, Rondon MUPB, Mano M, Hajjar LA, Hoff P, Filho R, Negrão CE Tags: Am J Physiol Heart Circ Physiol Source Type: research