Olanzapine induced autophagy through suppression of NF- κB activation in human glioma cells.

CONCLUSIONS: Our findings identify a pathway by which olanzapine induces autophagy by depressing NF-κB in a glioma cell line, providing evidence which supports the use of olanzapine as a potential anticancer drug.
PMID: 30955240 [PubMed - as supplied by publisher]

Source: CNS Neuroscience and Therapeutics - April 6, 2019 Category: Neuroscience Authors: Zhu Y, Zhao YF, Liu RS, Xiong YJ, Shen X, Wang Y, Liang ZQ Tags: CNS Neurosci Ther Source Type: research