Neuro-inflammation and anti-inflammatory treatment options for Alzheimer's disease.

Neuro-inflammation and anti-inflammatory treatment options for Alzheimer's disease.
Clin Biochem. 2019 Apr 04;:
Authors: Ozben T, Ozben S
Abstract
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive memory loss and dementia. The pathological characteristics of AD include the deposition of amyloid beta (Aβ), neurofibrillary tangles, and neuronal loss. There is evidence showing the involvement of inflammation in AD, including activated microglia within and surrounding senile plaques. Epidemiological studies suggest the use of anti-inflammatory drugs to reduce incidence of AD. However, clinical trials with anti-inflammatory drugs have not been successful.
PMID: 30954437 [PubMed - as supplied by publisher]

Source: Clinical Biochemistry - April 3, 2019 Category: Biochemistry Authors: Ozben T, Ozben S Tags: Clin Biochem Source Type: research