Reproductive Systemic Toxicity and Mechanism of Glucosides of Tripterygium wilfordii Hook. F. (GTW).

CONCLUSION: Tripterygium glycosides affected the estrus cycle in female rats and caused damage to the uterus; in male rats, the testicles and sperm were damaged. The mechanism of reproductive toxicity occurred through the secretion of multiple hormones.
PMID: 30814076 [PubMed - in process]

Source: Annals of Clinical and Laboratory Science - December 31, 2018 Category: Laboratory Medicine Authors: Guo J, Huang Y, Lei X, Zhang H, Xiao B, Han Z, Liang C, Yang W Tags: Ann Clin Lab Sci Source Type: research