FAPI-PET predicts treatment response in patients with rheumatoid arthritis
In this study, they further analyzed data from 19 patients to determine whether FAPI-PET could help predict treatment responses.
All of the patients had high or moderate disease activity and underwent PET/CT exams at baseline, as well as standard F-18 FDG PET/CT scans for comparison. Subsequent treatments included conventional DMARDs (including methotrexate, leflunomide, cyclophosphamide, and tripterygium wilfordii), and synthetic DMARDs (including etanercept, adalimumab, and Janus Kinase inhibitors). Six patients received additional prednisone, and six patients had nonsteroidal anti-inflammatory drugs.Representative Ga-6...
Source: AuntMinnie.com Headlines - January 9, 2024 Category: Radiology Authors: Will Morton Tags: Subspecialties Nuclear Radiology Source Type: news
Rat Infestations Are a Global Problem. Is Birth Control the Solution?
Not every politician is willing to admit they owe their election to rats. But Laura Mikulski, city councilwoman for Ferndale, Michigan isn’t shy about attributing her political career—literally—to skeevy, long-tailed rodents.
Mikulski, who educated herself in all things rat control, is the co-founder of the Ferndale Rat Patrol. She created a citizens’ movement to accurately assess the local scope of its burgeoning rat problem, embrace less environmentally harmful methods of pest control, and even host a month-long census, called Traptoberfest, in which participants win gold-painted spring trap trop...
Source: TIME: Science - March 27, 2023 Category: Science Authors: Lisa Abend Tags: Uncategorized animals feature freelance Source Type: news
Compound derived from thunder god vine could help pancreatic cancer patients
(The Translational Genomics Research Institute) The results of a pre-clinical study led by researchers at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest how a compound derived from the thunder god vine -- an herb used in China for centuries to treat joint pain, swelling and fever -- is able to kill cancer cells and potentially improve clinical outcomes for patients with pancreatic cancer. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - December 14, 2020 Category: Cancer & Oncology Source Type: news
Rheumatoid arthritis: Thunder god vine is comparable to drug treatments, research suggests
RHEUMATOID arthritis can be excruciating but you do not have to accept it as your lot. Thunder god vine supplementation has been proven to rival a standard rheumatoid arthritis drug in its ability to alleviate symptoms. (Source: Daily Express - Health)
Source: Daily Express - Health - November 30, 2020 Category: Consumer Health News Source Type: news
How celastrol sensitizes brains to leptin, curbing hunger and obesity
Celastrol's potent anti-obesity effects were widely reported in 2015. Derived from the roots of the thunder god vine, the drug curbed food intake in obese mice by nearly 80 percent, producing up to a 45 percent weight loss. Celastrol increases the brain's sensitivity to leptin, the hormone that signals we've had enough to eat, but until now, no one knew how. In today's Nature Medicine, a study led by Umut Ozcan, MD, at Boston Children's Hospital finally solves the mystery. (Source: World Pharma News)
Source: World Pharma News - March 4, 2019 Category: Pharmaceuticals Tags: Featured Research Research and Development Source Type: news
How celastrol sensitizes brains to leptin, curbing hunger and obesity
(Boston Children's Hospital) Celastrol's potent anti-obesity effects were widely reported in 2015. Derived from the roots of the thunder god vine, the drug curbed food intake in obese mice by nearly 80 percent, producing up to a 45 percent weight loss. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - March 4, 2019 Category: International Medicine & Public Health Source Type: news
Ancient thunder god vine could hold the cure to the obesity epidemic
Scientists from the German Center for Diabetes Research found that when the herbal extract celastrol is fed to obese mice, the rodents eat less, which causes them to shed the pounds. (Source: the Mail online | Health)
Source: the Mail online | Health - September 4, 2018 Category: Consumer Health News Source Type: news
Hope for plant-based contraceptive, study claims
Conclusion
This laboratory study aimed to investigate a variety of steroid hormones and plant compounds to look at their effect on sperm activation and ability to fertilise an egg.
The researchers confirmed that the hormone progesterone present in the female reproductive tract seems to be needed to activate sperm and make them able to fertilise an egg.
The also found that two plant compounds, pristimerin and lupeol, were able to block the sites on the sperm that are activated by progesterone. This means these two compounds could have a potential contraceptive action.
But it's far too early to say whether new contraceptiv...
Source: NHS News Feed - May 16, 2017 Category: Consumer Health News Tags: Pregnancy/child Source Type: news
Summary of Evidence: Musculoskeletal Inflammation and Natural Products
Learn what the science says about musculoskeletal inflammation and natural products in the current issue of NCCIH Clinical Digest. Read more about the evidence base of tumeric, bromelain, willow bark, Omega-3 fatty acids, devil’s claw, ginger and thunder god vine in the treatment of conditions like osteoarthritis, rheumatoid arthritis, and tendinitis. /da (Source: MCR News)
Source: MCR News - July 13, 2016 Category: Databases & Libraries Authors: liaison Tags: All Members Source Type: news
Fatal honey poisoning caused by Tripterygium wilfordii Hook F in Southwest China: a case series - Zhang Q, Chen X, Chen S, Liu Z, Wan R, Li J.
We describe a rare case series of fatal honey poisoning caused by Tripterygium wilfordii Hook F (TwHF) in Southwest China. Three male construction workers were deliver... (Source: SafetyLit)
Source: SafetyLit - May 12, 2016 Category: Global & Universal Tags: Home and Consumer Product Safety Source Type: news
Thunder God Vine Fizzles in Ankylosing Spondylitis (CME/CE)
(MedPage Today) -- Chinese herb falls short in meta-analysis of treatment efficacy (Source: MedPage Today State Required CME)
Source: MedPage Today State Required CME - August 25, 2015 Category: Consumer Health News Source Type: news
'Thunder god vine' may hold key to effective obesity drug
Stephen FellerBOSTON, May 22 (UPI) -- An extract called celastrol from the Chinese "thunder god vine" may help with weight loss by enhancing an appetite-suppressing hormone called leptin. (Source: Health News - UPI.com)
Source: Health News - UPI.com - May 22, 2015 Category: Consumer Health News Source Type: news
Is the thunder god vine the key to beating obesity? Ancient chinese remedy led to a 45% decrease in body weight in obese mice
An extract from the thunder god vine reduced food intake in obese mice, researchers found. Experts say it could lead to 'novel and powerful treatment for obesity'. (Source: the Mail online | Health)
Source: the Mail online | Health - May 22, 2015 Category: Consumer Health News Source Type: news
Thunder god vine used in traditional Chinese medicine is a potential obesity treatment
An extract from the thunder god vine, which has a long history of use in traditional Chinese medicine, reduces food intake and causes up to a 45 percent decrease in body weight in obese mice. The weight-loss compound, called Celastrol, produces its potent effects by enhancing the action of an appetite-suppressing hormone called leptin. The findings are an early indicator that Celastrol could be developed into a drug for the treatment of obesity. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 21, 2015 Category: Science Source Type: news
