The Birth of Angiotensin: An International Compromise.
The Birth of Angiotensin: An International Compromise.
Am J Med Sci. 2019 Mar;357(3):179-183
Authors: Smulyan H, Villarreal D
Abstract
Irvine Page in the United States and Eduardo Braun-Menéndez in Argentina led teams of investigators that studied the role of the kidney in blood pressure regulation. Contemporaneously in 1939, each team using different methods discovered and described a new substance now known as angiotensin. At the time of discovery, Page called it "angiotonin" and Braun-Menéndez called it "hipertensina," anglicized to "hypertensin." Over time, the importance of this substance in circulatory control, pathophysiology and pharmacology became indisputable and the need for a single name became obvious. In a remarkable accommodation, Page and Braun-Menéndez agreed to forego any claim to priority and chose a name with elements of both. Following this compromise, Page and Braun-Menéndez went on to become leaders in science in their own countries as well as recognition world-wide while, angiotensin and its derivatives have become standard components in the understanding and treatment of diseases of the heart, kidney and brain.
PMID: 30798942 [PubMed - in process]
Source: The American Journal of the Medical Sciences - Category: General Medicine Authors: Smulyan H, Villarreal D Tags: Am J Med Sci Source Type: research
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