Increased Dynamin ‐Related Protein 1‐Dependent Mitochondrial Fission Contributes to High‐Fat Diet‐Induced Cardiac Dysfunction and Insulin Resistance by Elevating Tafazzin in Mouse Hearts

ConclusionIn high ‐fat diet‐fed mouse hearts, increased tafazzin contributes to insulin resistance via mediating Drp‐1 translocation to the mitochondria, and a small non‐coding RNA, miR‐125b‐5p, at least partially regulates this signalling pathway and alleviates insulin resistance.This article is protected by copyright. All rights reserved

Source: Molecular Nutrition and Food Research - January 10, 2019 Category: Food Science Authors: Wenguang Chang, Dandan Xiao, Xiang Ao, Mengyang Li, Tao Xu, Jianxun Wang Tags: Research Article Source Type: research