Clinical and Genomic Implications of Luminal and Basal Subtypes Across Carcinomas.

CONCLUSIONS: This first pan-carcinoma luminal/basal subtyping across epithelial tumors reveals global similarities across carcinomas in the transcriptome, genome, clinical outcomes, and drug sensitivity, emphasizing the biological and translational importance of these luminal vs. basal subtypes.
PMID: 30573691 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - December 20, 2018 Category: Cancer & Oncology Authors: Zhao SG, Chen WS, Das R, Chang SL, Tomlins SA, Chou J, Quigley DA, Dang HX, Barnard TJ, Mahal BA, Gibb EA, Liu Y, Davicioni E, Duska LR, Posadas EM, Jolly S, Spratt DE, Nguyen PL, Maher CA, Small EJ, Feng FY Tags: Clin Cancer Res Source Type: research