Log in to search using one of your social media accounts:

 

Z-endoxifen shows promise as new treatment for common breast cancer type
(Mayo Clinic) ROCHESTER, Minn. - Z-endoxifen, a potent derivative of the drug tamoxifen, could itself be a new treatment for the most common form of breast cancer in women with metastatic disease. This finding was reported from a clinical trial conducted by researchers at Mayo Clinic and the National Cancer Institute, and published in the Journal of Clinical Oncology. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 30, 2017 Category: International Medicine & Public Health Source Type: news

Adjuvant Endocrine Therapy in Postmenopausal Breast Cancer
This video highlights trials studying the long-term impact of adjuvant tamoxifen and aromatase inhibitors for the treatment of patients with postmenopausal breast cancer. (Source: CancerNetwork)
Source: CancerNetwork - August 25, 2017 Category: Cancer & Oncology Authors: Prudence A. Francis, MD Tags: Videos Breast Cancer Source Type: news

Breast cancer wonder drug boosts IVF hopes
A British clinic is pioneering the use of tamoxifen - typically given to patients who have undergone breast cancer surgery - to help women aged over 40 who have a limited number of eggs. (Source: the Mail online | Health)
Source: the Mail online | Health - August 13, 2017 Category: Consumer Health News Source Type: news

Gene Score for Recurrence Risk in ER-Positive Breast Cancer Gene Score for Recurrence Risk in ER-Positive Breast Cancer
Can this gene recurrence score help determine which patients with ER-positive breast cancer are good candidates for radiotherapy after adjuvant chemotherapy plus tamoxifen?Journal of the National Cancer Institute (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - July 20, 2017 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

RCT: Menopause Symptoms Mistaken for Tamoxifen Side Effects RCT: Menopause Symptoms Mistaken for Tamoxifen Side Effects
Many women who use tamoxifen as a chemopreventive agent experience symptoms that are assumed to be drug related, but they may just be naturally occurring symptoms related to menopause.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - July 6, 2017 Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news

Many Women Have Questions, Concerns About Tamoxifen
Study shows that normal symptoms of menopause are often attributed to tamoxifen (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - June 30, 2017 Category: Cancer & Oncology Tags: Family Medicine, Gynecology, Internal Medicine, Nursing, Oncology, Pharmacy, Journal, Source Type: news

Many Women Mistaken on'Side Effects' of Breast Cancer Drug
Study shows that normal symptoms of menopause are often blamed on tamoxifen Source: HealthDay Related MedlinePlus Pages: Breast Cancer, Drug Reactions, Menopause (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - June 30, 2017 Category: Consumer Health News Source Type: news

Many Women Mistaken on ‘ Side Effects ’ of Breast Cancer Drug
Study shows that normal symptoms of menopause are often blamed on tamoxifen (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - June 29, 2017 Category: Cancer & Oncology Tags: Gynecology, Nursing, Oncology, Pharmacy, News, Source Type: news

Breast cancer: Women confuse menopause symptoms to anti-breast cancer drug side effects
WOMEN at high risk of breast cancer are not taking the preventative drug tamoxifen because they are confusing symptoms of the menopause with side-effects, a new study found. (Source: Daily Express - Health)
Source: Daily Express - Health - June 29, 2017 Category: Consumer Health News Source Type: news

Many Women Mistaken on'Side Effects' of Breast Cancer Drug
THURSDAY, June 29, 2017 -- Many women at high risk for breast cancer do not take the drug tamoxifen to prevent the disease, often because they confuse naturally occurring symptoms with side effects from the drug. That's the finding of a new study of... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - June 29, 2017 Category: General Medicine Source Type: news

Confusion over symptoms may be affecting whether women take tamoxifen for breast cancer
(Queen Mary University of London) Women who are at high risk of developing breast cancer may be failing to take the preventive anti-cancer drug tamoxifen because they are confusing naturally occurring symptoms with side effects from the medicine, according to a study of nearly 4,000 women led by Queen Mary University of London. (Source: EurekAlert! - Cancer)
Source: EurekAlert! - Cancer - June 29, 2017 Category: Cancer & Oncology Source Type: news

Systemic Therapy and Risk of Contralateral Breast Cancer Systemic Therapy and Risk of Contralateral Breast Cancer
After completing tamoxifen or chemotherapy, how long does risk reduction for contralateral breast cancer last?Breast Cancer Research (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 22, 2017 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

Tamoxifen protects against obesity-related metabolic disorders
Tamoxifen is the gold standard for endocrine treatment of estrogen-receptor positive breast cancer. Tamoxifen is also known to have metabolic effects. A new study reports that the drug also prevents obesity, fatty liver, and insulin resistance in female mice who were fed a high-fat diet and whose ovaries had been removed. The study was also able to pinpoint which estrogen receptors underlie these protective effects, opening up possibilities for new therapies to treat these conditions. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - May 11, 2017 Category: Science Source Type: news

Tamoxifen protects against obesity-related metabolic disorders
(Elsevier Health Sciences) Tamoxifen is the gold standard for endocrine treatment of estrogen-receptor positive breast cancer. Tamoxifen is also known to have metabolic effects. A new study in The American Journal of Pathology reports that the drug also prevents obesity, fatty liver, and insulin resistance in female mice who were fed a high-fat diet and whose ovaries had been removed. The study was also able to pinpoint which estrogen receptors underlie these protective effects, opening up possibilities for new therapies to treat these conditions. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - May 11, 2017 Category: International Medicine & Public Health Source Type: news

Prolonged Tamoxifen Surpasses Oophorectomy in Breast Cancer Prolonged Tamoxifen Surpasses Oophorectomy in Breast Cancer
For premenopausal women with estrogen receptor-positive breast cancer treated for 5 years with tamoxifen, lifetime outcomes are best with an extra 5 years of tamoxifen, a simulation model predicts.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 9, 2017 Category: Consumer Health News Tags: Ob/Gyn & Women ' s Health News Source Type: news

Mangosteen: The Cancer-Fighting Superfruit
  If you're a woman with a family history of breast cancer, your doctor may recommend you start taking a toxic chemo drug like tamoxifen to lower your risk of developing the disease. Even if you have no signs or symptoms of cancer. Tamoxifen is what's known as a chemopreventive agent. That's a fancy phrase that means it's something that prevents cancer from forming. But its track record isn't all that impressive. Trials found that for every 1,000 women who take the drugs, only 21 to 35 cases of cancer would be prevented. And the side effects are downright terrifying. Bone pain, blood clots, increas...
Source: Al Sears, MD Natural Remedies - March 23, 2017 Category: Complementary Medicine Authors: Cathy Card Tags: Anti-Aging Source Type: news

Breast cancer drug dampens immune response, protecting light-sensing cells of the eye
The breast cancer drug tamoxifen appears to protect light-sensitive cells in the eye from degeneration, according to a new study in mice. The drug prevented immune cells from removing injured photoreceptors, the light-sensitive cells of the retina in the back of the eye. The study, recently reported in theJournal of Neuroscience, suggests tamoxifen might work for the treatment of age-related macular degeneration (AMD) and retinitis pigmentosa (RP), blinding diseases that lack good treatment options. (Source: News from NEI)
Source: News from NEI - March 13, 2017 Category: Opthalmology Authors: balintfyj Source Type: news

Breast cancer drug dampens immune response, protecting light-sensing cells of the eye
The breast cancer drug tamoxifen appears to protect light-sensitive cells in the eye from degeneration, according to a new study in mice. The drug prevented immune cells from removing injured photoreceptors. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - March 13, 2017 Category: Science Source Type: news

Understanding GP attitudes to cancer preventing drugs
This report presents the results of a survey of GPs about their use of offering tamoxifen and aspirin to lower the risk of, or prevent, certain cancers. It found nearly half of GPs were unaware of the benefits of tamoxifen to prevent breast cancer. The report concludes more needs to be done to ensure GPs are given the support they need (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - February 28, 2017 Category: Consumer Health News Source Type: news

Understanding GP attitudes to cancer preventing drugs
A report from Cancer Research explores how much GPs know about two drugs that can reduce the risk of cancer – tamoxifen for women at high risk of breast cancer, and aspirin for people with Lynch Syndrome, a condition that increases the risk of several types of cancer. (Source: NHS Networks)
Source: NHS Networks - February 16, 2017 Category: UK Health Source Type: news

[Editors' Choice] Tamoxifen as an immunotherapy
Antiestrogen drugs may treat some estrogen receptor-negative tumors by limiting the proliferation and activity of suppressive immune cells. (Source: Signal Transduction Knowledge Environment)
Source: Signal Transduction Knowledge Environment - February 15, 2017 Category: Science Authors: Nancy Gough (mailto:ngough at aaas.org) Source Type: news

GPs 'failing to prescribe tamoxifen to prevent breast cancer'
Conclusion This large survey shows around half of GPs surveyed were unaware of the benefits of tamoxifen: namely, that the drug can reduce the risk of breast cancer in women with a family history of the condition. Only around a quarter of GPs surveyed were aware of the current UK guidelines. Researchers found GPs were more likely to feel comfortable carrying on a prescription initiated by hospital doctors, rather than being the one to take the decision to prescribe. This is perhaps unsurprising given that the drug is still not licensed for the primary prevention of cancer. NICE currently recommends prescribers need to ta...
Source: NHS News Feed - February 14, 2017 Category: Consumer Health News Tags: Cancer Medication Medical practice Source Type: news

Ignorant GPs deny patients drugs that ward off cancer
Two major UK studies have shown many GPs are unaware that prescribing certain patients daily pills - such as tamoxifen and aspirin - can slash their odds of developing certain tumours. (Source: the Mail online | Health)
Source: the Mail online | Health - February 14, 2017 Category: Consumer Health News Source Type: news

Work needed to boost GPs ’ knowledge of cancer drug
Only a quarter of GPs aware of NICE guideline on tamoxifen Related items fromOnMedica Tamoxifen linked to reduced contralateral breast cancer risk One in six breast cancer patients have symptom other than a lump Big data advances breast cancer research by ‘decades’ (Source: OnMedica Latest News)
Source: OnMedica Latest News - February 13, 2017 Category: UK Health Source Type: news

Secondary care support can boost GP use of breast cancer prevention drug
Researchers have called for a joint primary and secondary care pathway to encourage prescribing of tamoxifen as a preventative treatment for women at increased risk of breast cancer. (Source: GP Online News)
Source: GP Online News - February 13, 2017 Category: Primary Care Tags: 12 Care of People with Cancer and Palliative Care Source Type: news

Older women less likely to be offered breast reconstruction after mastectomy
Guidelines state that surgeons should discuss breast reconstruction with all suitable patients Related items fromOnMedica Tamoxifen linked to reduced contralateral breast cancer risk Big data advances breast cancer research by ‘decades’ Breast conservation beats mastectomy for some patients Schoolboy youngest in UK to undergo mastectomy Study finds overuse of double mastectomy (Source: OnMedica Latest News)
Source: OnMedica Latest News - February 8, 2017 Category: UK Health Source Type: news

Black Women Face Devastating Losses If Obamacare Is Repealed
Bianca Adams worked part-time jobs as a spa professional, sometimes juggling two or three at a time, for years. But none of them offered her insurance, which meant that the 47-year-old with diabetes often went to the emergency room for care. “I was one of those people that had to go to the emergency when my blood sugar got too high and I needed fluids,” Adams told The Huffington Post. “There was really no one managing my health at that point.” When her Medicaid coverage through the Affordable Care Act began in 2014, Adams, who has been disabled with severe knee problems for 25 years, under...
Source: Healthy Living - The Huffington Post - February 4, 2017 Category: Consumer Health News Source Type: news

How Soy Can Both Prevent Breast Cancer And Fuel Its Spread
To eat soy or not: That’s the question many U.S. women have been asking. Tofu, miso paste and other soybean-based foods are high-quality sources of protein that are low in calories and saturated fat. And studies have shown that they can help prevent cancer. Yet many doctors recommend that women who have, or are at risk of developing, a common form of breast cancer called estrogen-receptor-positive breast cancer avoid eating soybean-based foods because they contain compounds called isoflavones. Some studies suggest that isoflavones can mimic the hormone estrogen and encourage tumor growth. Now, in an animal study, res...
Source: Healthy Living - The Huffington Post - February 3, 2017 Category: Consumer Health News Source Type: news

How Soy Can Both Prevent Breast Cancer And Fuel Its Spread
To eat soy or not: That’s the question many U.S. women have been asking. Tofu, miso paste and other soybean-based foods are high-quality sources of protein that are low in calories and saturated fat. And studies have shown that they can help prevent cancer. Yet many doctors recommend that women who have, or are at risk of developing, a common form of breast cancer called estrogen-receptor-positive breast cancer avoid eating soybean-based foods because they contain compounds called isoflavones. Some studies suggest that isoflavones can mimic the hormone estrogen and encourage tumor growth. Now, in an animal study, res...
Source: Science - The Huffington Post - February 3, 2017 Category: Science Source Type: news

Many Breast Cancer Survivors Don't Get Life-Extending Therapy
THURSDAY, Feb. 2, 2017 -- Hormonal therapies such as tamoxifen, or a class of drugs called aromatase inhibitors, can reduce the likelihood that women diagnosed with certain breast cancers will experience a recurrence of their disease. However, a... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - February 2, 2017 Category: Journals (General) Source Type: news

Initiating tamoxifen in secondary care increases GP prescribing
(Source: PharmacoEconomics and Outcomes News)
Source: PharmacoEconomics and Outcomes News - January 31, 2017 Category: Drugs & Pharmacology Source Type: news

New insights into why breast cancer drugs fail for some women
Conclusion This laboratory study aimed to investigate the mechanism behind how some oestrogen receptor-positive breast cancer tumours develop resistance to the hormone drugs tamoxifen and aromatase inhibitors. This resistance effectively makes these drugs powerless, causing the cancer to return. The researchers seemed to find at least part of the answer as to why resistance to aromatase inhibitors can develop. In some cases, they found treatment triggered the amplification of the CYP19A1 gene, which increased the production of aromatase, essentially allowing the cells to keep making their own oestrogen. But this doesn't...
Source: NHS News Feed - January 24, 2017 Category: Consumer Health News Tags: Cancer Medication Genetics/stem cells Source Type: news

Menopause Symptoms Can Predict Tamoxifen Adherence for Breast Cancer Prevention
This video examines findings from the International Breast Cancer Intervention Study (IBIS-1), which found that patients with menopause symptoms were less likely to continue long-term tamoxifen therapy. (Source: CancerNetwork)
Source: CancerNetwork - January 14, 2017 Category: Cancer & Oncology Authors: Samuel Smith, PhD Tags: Videos Breast Cancer Source Type: news

Aromatase inhibitors for breast cancer: Advantages over tamoxifen in early-stage disease
Patients survive longer, recurrences occur later, and certain side effects occur less often. Overall, the evidence for late-stage disease is much poorer. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 29, 2016 Category: Science Source Type: news

Aromatase inhibitors for breast cancer: Advantages over tamoxifen in early-stage disease
(Institute for Quality and Efficiency in Health Care) Patients survive longer, recurrences occur later, and certain side effects occur less often. Overall, the evidence for late-stage disease is much poorer. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 29, 2016 Category: Global & Universal Source Type: news

Researchers use nanoparticles to overcome treatment-resistant breast cancer
Researchers from the University of Cincinnati College of Medicine have developed RNA nanoparticles that show promise in overcoming treatment-resistant breast cancer. The team’s work was published in ACS Nano.  The researchers used a nanocarrier to target HER2-positive breast cancer and stop the production of a specific protein to prevent metastasis and render the cancer cells vulnerable to tamoxifen, a therapy for estrogen-driven cancer. Get the full story at our sister site, Drug Delivery Business News. The post Researchers use nanoparticles to overcome treatment-resistant breast cancer appe...
Source: Mass Device - December 15, 2016 Category: Medical Equipment Authors: Sarah Faulkner Tags: Drug-Device Combinations Oncology Pharmaceuticals Research & Development University of Cincinnati Source Type: news

Breast cancer patients fail to complete tamoxifen therapy
Around 20% of breast cancer patients do not complete prescribed endocrine therapy, such as tamoxifen, according to researchers. (Source: Nursing Times)
Source: Nursing Times - December 14, 2016 Category: Nursing Source Type: news

Menopausal Symptoms Cut Tamoxifen Adherence (CME/CE)
(MedPage Today) -- Headaches and nausea/vomiting were particularly problematic (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - December 11, 2016 Category: Journals (General) Source Type: news

Tamoxifen may get blamed for unrelated symptoms
HealthDay News Some women who take tamoxifen to prevent breast cancer may mistake naturally occurring nausea and vomiting for side effects and stop taking it, a study finds. (Source: Health News - UPI.com)
Source: Health News - UPI.com - December 9, 2016 Category: Consumer Health News Source Type: news

Naturally occurring symptoms may be mistaken for tamoxifen side-effects
Women taking tamoxifen to prevent breast cancer were less likely to continue taking the drug if they suffered nausea and vomiting, according to new  data. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 9, 2016 Category: Science Source Type: news

Tamoxifen May Get Blamed for Unrelated Symptoms
Perceived side effects might lead some to stop taking the breast cancer preventative, study finds (Source: The Doctors Lounge - Oncology)
Source: The Doctors Lounge - Oncology - December 9, 2016 Category: Cancer & Oncology Authors: webmaster at doctorslounge.com Tags: Gynecology, Nursing, Oncology, Pharmacy, News, Source Type: news

Women wrongly stop taking breast cancer drug Tamoxifen because of 'side effects'
A Cancer Research UK study has found that women taking dummy drugs are just as likely to suffer nausea and vomiting as those taking tamoxifen, and are just as likely to stop taking them. (Source: the Mail online | Health)
Source: the Mail online | Health - December 9, 2016 Category: Consumer Health News Source Type: news

Tamoxifen May Get Blamed for Unrelated Symptoms
Perceived side effects might lead some to stop taking the breast cancer preventative, study finds (Source: WebMD Health)
Source: WebMD Health - December 9, 2016 Category: Consumer Health News Source Type: news

Symptoms may be ‘mistaken’ for tamoxifen side effects
Naturally occurring symptoms may be mistaken for side-effects of a common drug that may result in them wrongly stopping treatment, according to a UK study. (Source: Nursing Times)
Source: Nursing Times - December 9, 2016 Category: Nursing Source Type: news

Breast cancer drug: Cancer prevention pill Tamoxifen might NOT cause nasty side-effects
TAMOXIFEN is a hormone therapy for breast cancer which reduces the risk of the disease coming back after surgery. However, experts have revealed some women are stopping taking the drug because they mistakenly believe it is causing unpleasant side-effects, research has revealed. (Source: Daily Express - Health)
Source: Daily Express - Health - December 9, 2016 Category: Consumer Health News Source Type: news

Breast cancer drug update: Cancer prevention pill Tamoxifen may NOT cause side-effects
TAMOXIFEN is a hormone therapy for breast cancer which reduces the risk of the disease coming back after surgery. However, experts have revealed some women are stopping taking the drug because they mistakenly believe it is causing unpleasant side-effects, research has revealed. (Source: Daily Express - Health)
Source: Daily Express - Health - December 9, 2016 Category: Consumer Health News Source Type: news

Tamoxifen May Get Blamed for Unrelated Symptoms
FRIDAY, Dec. 9, 2016 -- Some high-risk women who take tamoxifen to prevent breast cancer may mistake naturally occurring nausea and vomiting for side effects of the drug and stop taking it, a new study finds. Previous research has shown that taking... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - December 9, 2016 Category: Journals (General) Source Type: news

Tamoxifen May Get Blamed for Unrelated Symptoms
Title: Tamoxifen May Get Blamed for Unrelated SymptomsCategory: Health NewsCreated: 12/9/2016 12:00:00 AMLast Editorial Review: 12/9/2016 12:00:00 AM (Source: MedicineNet Cancer General)
Source: MedicineNet Cancer General - December 9, 2016 Category: Cancer & Oncology Source Type: news

Naturally occurring symptoms may be mistaken for tamoxifen side-effects
(Cancer Research UK) Women taking tamoxifen to prevent breast cancer were less likely to continue taking the drug if they suffered nausea and vomiting, according to new data presented at the San Antonio Breast Cancer Symposium. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - December 9, 2016 Category: Global & Universal Source Type: news