Prevalence and Clinical Characteristics of False-Positive Aspergillus Galactomannan Test in Healthy Subjects and Patients with Hematologic Malignancies

Conclusions: Our findings revealed significantly high frequencies of false-positive GM test results in the elderly and in men among healthy subjects. We also found a significantly higher frequency of false-positive GM test results in patients with MM, especially in those with IgG-type myeloma, when compared with patients having lymphoid and myeloid neoplasia. These results indicated that careful interpretation of the GM test results may be required in these populations in the assessment of possible aspergillosis. Further studies are required to validate our results and elucidate the mechanisms of these phenomena.DisclosuresNo relevant conflicts of interest to declare.

Source: Blood - November 21, 2018 Category: Hematology Authors: Abe, Y., Narita, K., Kobayashi, H., Kitadate, A., Takeuchi, M., Matsue, K. Tags: 203. Lymphocytes, Lymphocyte Activation, and Immunodeficiency, including HIV and Other Infections: Poster II Source Type: research