Invasive aspergillosis in critically ill patients: Review of definitions and diagnostic approaches
Invasive aspergillosis (IA) is an increasingly recognised phenomenon in critically ill patients in the intensive care unit, including in patients with severe influenza and severe coronavirus disease 2019 (COVID-19) infection. To date, there are no consensus criteria on how to define IA in the ICU population, although several criteria are used, including the AspICU criteria and new consensus criteria to categorise COVID-19-associated pulmonary aspergillosis (CAPA). In this review, we describe the epidemiology of IA in critically ill patients, most common definitions used to define IA in this population, and most common clin...
Source: Current Awareness Service for Health (CASH) - September 10, 2021 Category: Consumer Health News Source Type: news

Evaluation of a Prototype of a Novel Galactomannan Sandwich Assay Using the VIDAS ® Technology for the Diagnosis of Invasive Aspergillosis
Conclusions: This new VIDAS ® GM prototype assay showed adequate analytical and clinical performance and a good correlation with that of Platelia ™ Aspergillus Ag with 126 sera, although these results need to be confirmed in a larger prospective and multicentric study. As for the other VIDAS ® assays, VIDAS ® GM is a single-sample automated test using a solid reagent strip and receptacle. It is easy to use and suitable for rapid on-demand test results. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - August 12, 2021 Category: Consumer Health News Source Type: news

Green fungus now a major threat after Covid recovery
While mucormycosis affects sinuses, aspergillosis affects the lungs of a patient. It is not as severe a disease as mucormycosis, which requires debulking surgeries (surgical removal of affected tissue including in eye). (Source: The Economic Times)
Source: The Economic Times - June 30, 2021 Category: Consumer Health News Source Type: news

Invasive Aspergillosis Due to Aspergillus Section Usti: A Multicenter Retrospective Study, Clinical Infectious Diseases
Conclusions Aspergillus ustus IA mainly occurred in nonneutropenic transplant patients and was frequently associated with extrapulmonary sites of infection. Mortality rate was high and optimal antifungal therapy remains to be defined. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - May 13, 2021 Category: Consumer Health News Source Type: news

Digestive enzymes of fungal origin as a relevant cause of false positive Aspergillus antigen testing in intensive care unit patients, Infection
Background: Galactomannan antigen (GM) testing is widely used in the diagnosis of invasive aspergillosis (IA). Digestive enzymes play an important role in enzyme substitution therapy in exocrine pancreatic insufficiency. As digestive enzymes of fungal origin like Nortase contain enzymes from Aspergillus, a false-positive result of the test might be possible because of cross-reacting antigens of the cell wall of the producing fungi. We, therefore, asked whether the administration of fungal enzymes is a relevant cause of false-positive GM antigen test results. Methods: Patients with a positive GM antigen test between January...
Source: Current Awareness Service for Health (CASH) - May 13, 2021 Category: Consumer Health News Source Type: news

Aspergillus Polymerase Chain ReactionAn Update on Technical Recommendations, Clinical Applications, and Justification for Inclusion in the Second Revision of the EORTC/MSGERC Definitions of Invasive Fungal Disease, Clinical Infectious Diseases
Aspergillus polymerase chain reaction testing of blood and respiratory samples has recently been included in the second revision of the EORTC/MSGERC definitions for classifying invasive fungal disease. This is a result of considerable efforts to standardize methodology, the availability of commercial assays and external quality control programs, and additional clinical validation. This supporting article provides both clinical and technical justifications for its inclusion while also summarizing recent advances and likely future developments in the molecular diagnosis of invasive aspergillosis. (Source: Current Awareness S...
Source: Current Awareness Service for Health (CASH) - April 15, 2021 Category: Consumer Health News Source Type: news

Invasive pulmonary aspergillosis after treatment with tocilizumab in a patient with COVID-19 ARDS: a case report, Diagnostic microbiology and infectious disease
We present the case of a previously immunocompetent man with coronavirus disease-2019 who developed invasive pulmonary aspergillosis after treatment with tocilizumab, illustrating the importance of considering opportunistic infections when providing immune modulating therapy. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - April 15, 2021 Category: Consumer Health News Source Type: news

COVID-19-Associated Pulmonary Aspergillosis COVID-19-Associated Pulmonary Aspergillosis
A new report provides insight into the incidence of pulmonary aspergillosis among COVID-19 patients.Emerging Infectious Diseases (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - April 15, 2021 Category: Intensive Care Tags: Infectious Diseases Journal Article Source Type: news

Breakthrough in developing new diagnostic procedure for pulmonary aspergillosis
(University of Exeter) Scientists have developed a pioneering new procedure that will help diagnose a potentially lethal fungal lung disease with greater speed and accuracy, and with less distress to the patient. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - March 23, 2021 Category: Infectious Diseases Source Type: news

Allergic Bronchopulmonary Aspergillosis During COVID-19 Allergic Bronchopulmonary Aspergillosis During COVID-19
This unusual case highlights the role home isolation can have in the development of Aspergillus-associated respiratory disorders, particularly during the current COVID-19 pandemic.BMC Pulmonary Medicine (Source: Medscape Radiology Headlines)
Source: Medscape Radiology Headlines - January 26, 2021 Category: Radiology Tags: Pulmonary Medicine Journal Article Source Type: news

Aspergillosis Complicating Severe Coronavirus Disease Aspergillosis Complicating Severe Coronavirus Disease
A new report provides insight into the pathophysiology, diagnosis, and outcomes of coronavirus-associated pulmonary aspergillosis.Emerging Infectious Diseases (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 12, 2021 Category: Consumer Health News Tags: Infectious Diseases Journal Article Source Type: news

Killer lung infection that lurks in your compost
The illness - called invasive aspergillosis - develops when tiny particles of a common fungus are inhaled into the lungs, causing an infection. (Source: the Mail online | Health)
Source: the Mail online | Health - September 19, 2020 Category: Consumer Health News Source Type: news

Successful treatment of allergic bronchopulmonary aspergillosis with benralizumab after no response to omalizumab
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - August 22, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Effects of omalizumab in allergic bronchopulmonary aspergillosis in 10 asthmatic patients
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - August 22, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Differences in clinical characteristics between aspergillus fumigatus sensitized asthmatics and allergic bronchopulmonary aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - August 20, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Allergic bronchopulmonary aspergillosis (ABPA) and omalizumab treatment
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - August 20, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Allergic bronchopulmonary aspergillosis as a complication of COPD: A new entity
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - August 20, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

The potential diagnostic value of periostin in patients with allergic bronchopulmonary aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - August 20, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Clinical and immunological characteristics of fungal sensitive asthma and allergic bronchopulmonary Aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - August 20, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Invasive Pulmonary Aspergillosis Common in Intubated COVID-19 Patients Invasive Pulmonary Aspergillosis Common in Intubated COVID-19 Patients
More than a quarter of intubated patients with COVID-19 have evidence of invasive pulmonary aspergillosis, according to a new study.Reuters Health Information (Source: Medscape Critical Care Headlines)
Source: Medscape Critical Care Headlines - August 14, 2020 Category: Intensive Care Tags: Infectious Diseases News Source Type: news

Case series of Allergic Bronchopulmonary Aspergillosis (ABPA) and patients with severe Asthma fungi sensitized in a national institute of pulmonary diseases in Mexico
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - August 5, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

In vivo efficacy of NP339 against Invasive Pulmonary Aspergillosis (IPA)
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - July 2, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Efficacy and Safety of Posaconazole versus Voriconazole for the Treatment of Invasive Aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - July 2, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

The burden of chronic pulmonary aspergillosis on the respiratory service at a district general hospital
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - July 2, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Incidence, risk factors and clinical impact of invasive pulmonary aspergillosis in patients hospitalised with influenza infection
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - July 2, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Diagnostics and treatment of invasive aspergillosis in B-cell lymphoma patients after cytostatic chemotherapy and autologous stem cell transplantation
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - July 2, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

The emerging non-conventional invasive aspergillosis: 5-year experience
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - July 2, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Aspergillosis complicating severe influenza in intensive care unit patients: a retrospective case-control study
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - July 2, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Keep the attention high on Putative Invasive Pulmonary Aspergillosis (PIPA) in medical wards and intensive care units: a four-year retrospective analysis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - July 2, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Invasive aspergillosis and influenza virus infection: an accidental relationship?
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - July 1, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Proposition of a uniform methodological approach to attribution of invasive aspergillosis as a cause of death
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - July 1, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Clinical evaluation of a novel chemiluminescent microparticle immunoassay of Aspergillus galactomannan in diagnosis of invasive aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 30, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Clinical and laboratory features of mixed invasive mycoses in adult haematologic patients with invasive aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 24, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

A Gain-of-Function Polymorphism of CARD9 P.ser12asn Controls Allergic Bronchopulmonary Aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 22, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

A Challenging Case of Concurrent Nontuberculous Mycobacteria and Allergic Bronchopulmonary Aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 22, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Bronchodilator Response in Cystic Fibrosis Patients Diagnosed with Allergic Bronchopulmonary Aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 22, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Targeting Eosinophils in Allergic Bronchopulmonary Aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 22, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

The Role of Heme Uptake and Hemopexin in Invasive Pulmonary Aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 21, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Utility of Bronchoalveolar Lavage Galactomannan Assay in the Diagnosis of Invasive Pulmonary Aspergillus Infection in Immunocompetent Patients
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 21, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Aspergillosis in the Presence of Squamous Cell Carcinoma
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 21, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Allergic Bronchopulmonary Aspergillosis in an Octogenarian
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - June 21, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Knowledge of Aspergillosis Complicating Influenza Knowledge of Aspergillosis Complicating Influenza
How much do physicians know about pulmonary aspergillosis in patients with influenza, and what knowledge gaps remain?Emerging Infectious Diseases (Source: Medscape Allergy Headlines)
Source: Medscape Allergy Headlines - May 8, 2020 Category: Allergy & Immunology Tags: Infectious Diseases Journal Article Source Type: news

Invasive aspergillosis in COVID-19 patients
Tue, 03/31/2020 - 11:28News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - March 31, 2020 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Invasive aspergillosis after non-fatal drowning - Koide S, Hadano Y, Mizuochi S, Koga H, Yamashita H.
BACKGROUND: Pneumonitis and pneumonia after non-fatal drowning are common and the pathogens involved are numerous. However, invasive aspergillosis after non-fatal drowning in immunocompetent individuals is relatively rare. Here, we report a case of invasiv... (Source: SafetyLit)
Source: SafetyLit - March 28, 2020 Category: International Medicine & Public Health Tags: Drowning, Suffocation Source Type: news

Claims that child deaths caused by invasive aspergillosis were'not properly investigated' at top hospital
Claims that child deaths caused by invasive aspergillosis were'not properly investigated' at top hospitalWed, 03/18/2020 - 10:38News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - March 18, 2020 Category: Respiratory Medicine Authors: helenfindon Source Type: news

Many Clinicians Unaware of Invasive Pulmonary Aspergillosis
THURSDAY, March 12, 2020 -- Many clinicians are unaware of invasive pulmonary aspergillosis (IPA) after severe influenza, with few using galactomannan testing in intensive care unit (ICU) patients with severe influenza and worsening respiratory... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - March 12, 2020 Category: Pharmaceuticals Source Type: news

Aspergillus ustus and Invasive Aspergillosis
Fri, 03/06/2020 - 15:05News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - March 6, 2020 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Challenge for chronic pulmonary aspergillosis – a common but formidable disease
Challenge for chronic pulmonary aspergillosis – a common but formidable diseaseTuesday, March 3, 2020 - 16:39Slide presentation (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - March 3, 2020 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Allergic Bronchopulmonary Aspergillosis (ABPA) Related Admissions in the United States and It's Outcomes in Asthmatics
Allergic Bronchopulmonary Aspergillosis (ABPA) Related Admissions in the United States and It's Outcomes in AsthmaticsConference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - March 2, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news

Multidisciplinary Management of Rapidly Progressive Mycobacterium Abscessus in a Patient with a New Diagnosis of Allergic Bronchopulmonary Aspergillosis
Conference abstracts (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - March 2, 2020 Category: Respiratory Medicine Authors: MeganB Source Type: news