Did Ötzi the Iceman have aspergillosis?
Wed, 10/25/2017 - 12:46News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 25, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Chronic Pulmonary Aspergillosis IV
Monday, October 16, 2017 - 08:36Slide presentation (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 16, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

Chronic Pulmonary Aspergillosis III
Monday, October 16, 2017 - 08:35Slide presentation (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 16, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

Chronic Pulmonary Aspergillosis II
Monday, October 16, 2017 - 08:34Slide presentation (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 16, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

Chronic Pulmonary Aspergillosis I
Monday, October 16, 2017 - 08:32Slide presentation (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 16, 2017 Category: Respiratory Medicine Authors: ROrritt Source Type: news

Efficacy of ambruticin analogs in a murine model of invasive pulmonary aspergillosis
Ambruticins are a family of polyketides. The antifungal activity of an ambruticin,KOSN-2079, was tested in the mouse model of invasive aspergillosis.KOSN-2079 significantly reduced pulmonary fungal burdens and improved survival over that with the vehicle control. These results support the continued development of ambruticins as antifungal agents. (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 11, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Efficacy of the investigational echinocandin ASP9726 in a guinea pig model of invasive pulmonary aspergillosis
ASP9726 is an investigational echinocandin with in vitro activity against Aspergillus species. We evaluated the pharmacokinetics and efficacy of this agent in an established guinea pig model of invasive pulmonary aspergillosis.ASP9726 plasma concentrations were measured in guinea pigs administered either a single dose or multiple doses of this agent at 2.5, 5, and 10 mg/kg of body weight/day by subcutaneous injection. Immunosuppressed guinea pigs were inoculated with A. (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - October 10, 2017 Category: Respiratory Medicine Authors: BethBradshaw Source Type: news

Researchers help develop new antifungal drug
(University of Liverpool) University researchers, working with F2G Limited (Eccles, Manchester), have developed a new antifungal drug to help in the treatment of life threatening invasive fungal infections such as invasive aspergillosis. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 6, 2017 Category: International Medicine & Public Health Source Type: news

8th Advances Against Aspergillosis: scholarship application deadline
Date: Wednesday, September 20, 2017Year: 2018Location: Lisbon, PortugalContent-type: current_conferences (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - September 20, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

8th Advances Against Aspergillosis: abstract submissions deadline
Date: Wednesday, September 20, 2017Year: 2018Location: Lisbon, Portugal.Content-type: current_conferences (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - September 20, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Management of allergic and chronic pulmonary aspergillosis: part 3
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - September 19, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Disease Maps: Aspergillosis Stakeholders
News blog (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - September 13, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Map of People with Aspergillosis
Add yourself to our worldwide map - no real names needed!World map of Aspergillosis (Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - September 11, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news

Sterilizing immunity in the lung relies on targeting fungal apoptosis-like programmed cell death
Humans inhale mold conidia daily and typically experience lifelong asymptomatic clearance. Conidial germination into tissue-invasive hyphae can occur in individuals with defects in myeloid function, although the mechanism of myeloid cell–mediated immune surveillance remains unclear. By monitoring fungal physiology in vivo, we demonstrate that lung neutrophils trigger programmed cell death with apoptosis-like features in Aspergillus fumigatus conidia, the most prevalent human mold pathogen. An antiapoptotic protein, AfBIR1, opposes this process by inhibiting fungal caspase activation and DNA fragmentation in the murin...
Source: ScienceNOW - September 7, 2017 Category: Science Authors: Shlezinger, N., Irmer, H., Dhingra, S., Beattie, S. R., Cramer, R. A., Braus, G. H., Sharon, A., Hohl, T. M. Tags: Immunology reports Source Type: news

Global Aspergillosis Statistics
(Source: The Aspergillus Website - updates)
Source: The Aspergillus Website - updates - July 20, 2017 Category: Respiratory Medicine Authors: GAtherton Source Type: news