Fatal aspergillosis of the renal vasculature in a combined liver-kidney transplant recipient

We report a case of 12-year-old female with primary hyperoxaluria with regular haemodialysis for the end-stage renal disease. She underwent a combined liver and renal transplantation which got infected by aspergillosis. In this case study, it is speculated that the most likely source of Aspergillus was contaminated preservative solution (perfusate), resulting in infection within the donor kidney and subsequent systemic infection in the recipient. This case study calls for critical analysis and needs for the routine culture of the preservative solution before transplantation, to detect any fungal contamination and manage it prophylactically.

Source: Indian Journal of Medical Microbiology - November 14, 2018 Category: Microbiology Authors: Vasant Nagvekar Chandrasekar H Pranatharthi Ram Gopalakrishnan Ramamurthy Anand Vidya Devarajan Mandayam Thirunarayan Anil Tarigopula Source Type: research