18F-FDG PET/CT in Autosomal Dominant Polycystic Kidney Disease Patients with Suspected Cyst Infection

Conclusion: 18F-FDG PET/CT is a useful imaging modality for the evaluation of patients with ADPKD and suspected cyst infection.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Clinical Source Type: research

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Which CKD patients may need measured GFR -- and why? A new review examines the question.Nephrology Dialysis Transplantation
Source: Medscape Today Headlines - Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news
AbstractHereditary spastic paraplegias (HSP) share as cardinal feature progressive spastic gait disorder. SPG4 accounts for about 25% of cases and is caused by mutations in theSPAST gene. Although HSP is an upper motor neuron disease, the relevance of non-motor symptoms is increasingly recognized because of the potential response to treatment. Our study sets out to evaluate non-motor symptoms and their relevance with regard to health-related quality of life. In 118 genetically confirmed SPG4 cases and age- and gender-matched controls, validated questionnaires were used to evaluate fatigue, depression, pain, and restless le...
Source: Journal of Neurology - Category: Neurology Source Type: research
AbstractWe performed a prospective study to evaluate the types and characteristics of central nervous system (CNS) disorders in patients after hematopoietic stem cell transplantation. The study included 163 episodes of CNS disorders of which 58 (36%) were infections. Proven or probable infections were documented in 34 patients and included fungi (n = 10, 29%), viruses (n = 12, 35%),Toxoplasma spp. (n = 9, 27%) and bacteria (n = 3, 9%). Non-infectious neurological disorders (n = 105, 64%) frequently encompassed metabolic/drug-induced abnormalities (n&thin...
Source: Journal of Neurology - Category: Neurology Source Type: research
AbstractBackground and purposeClinical outcome after endovascular thrombectomy in patients with acute ischemic stroke still varies significantly. Higher blood glucose levels (BGL) have been associated with worse clinical outcome, but the pathophysiological causes are not yet understood. We hypothesized that higher levels of BGL are associated with more pronounced ischemic brain edema and worse clinical outcome mediated by cerebral collateral circulation.Methods178 acute ischemic stroke patients who underwent mechanical thrombectomy were included. Early ischemic brain edema was determined using quantitative lesion water upt...
Source: Journal of Neurology - Category: Neurology Source Type: research
This study aimed to determine factors that may influence levels of daytime sleepiness and fatigue in a large cohort of DM1 patients followed for 9 years.MethodsThis study included 115 patients with DM1 at baseline (Time 1,T1) and at Time 2 (T2) who were questioned for daytime sleepiness, fatigue, history of depression, psychological distress, pain, hypothyroidism, and sleep habits. Also, their muscular impairment and intellectual quotient were evaluated. Regression models were used to identify correlates of daytime sleepiness and fatigue while controlling for time effect.ResultsBoth daytime sleepiness and fatigue incr...
Source: Journal of Neurology - Category: Neurology Source Type: research
Two Japanese nationals evacuated on the first chartered flight from Wuhan, epicenter of the coronavirus epidemic, have pneumonia symptoms but a coronavirus diagnosis has not been confirmed, hospital representatives said on Wednesday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Publication date: Available online 29 January 2020Source: IDCasesAuthor(s): Syuichi Tetsuka, Tomohiro Suzuki, Tomoko Ogawa, Ritsuo Hashimoto, Hiroyuki KatoAbstractThe aging phenomenon of tuberculosis (TB) patients is recognized all over the world, but no country is as prominent as Japan. Central nervous system (CNS) TB includes clinical entities: tuberculous meningitis, intracranial tuberculoma, and clinical features of CNS TB in the elderly may be atypical, non-specific, and confused with concomitant age-related diseases. Atypical clinical manifestations of TB in older persons can result in delay in diagnosis and initiati...
Source: IDCases - Category: Infectious Diseases Source Type: research
Publication date: Available online 29 January 2020Source: IDCasesAuthor(s): Sunish Shah, Marjorie Golden, Jeffrey E. Topal, Dayna McManusAbstractA 78 year old man developed a methicillin sensitive Staphylococcus aureus (MSSA) post-operative wound infection following an elective L2-L4 laminectomy. He was treated with surgical debridement which was to be followed by a planned 6 weeks course of cefazolin. However, two weeks post debridement, a follow-up MRI revealed an L3-L5 epidural abscess, septic arthritis and vertebral osteomyelitis prompting repeat surgical debridement. No purulence was noted, and operative cultur...
Source: IDCases - Category: Infectious Diseases Source Type: research
CONCLUSION: Our results indicate the potential role of immediate (5 min) or early (15 min) acquisition in replacement of standardized 240 minutes acquisition in PD patients, but this result is not confirmed in HF patients, in which the acquisition at 240 min is confirmed as the most affordable timing for image interpretation, emphasizing the different pathophysiology that underlies these two pathologies. PMID: 31985388 [PubMed - as supplied by publisher]
Source: Current Radiopharmaceuticals - Category: Radiology Tags: Curr Radiopharm Source Type: research
When Justin Steece ventures out of his apartment in Wuhan, his primary worry isn’t getting sick. He’s more concerned that he might bring the deadly pneumonia-like virus circulating the city back home to his wife and newborn baby. But with supplies of infant formula getting low, Steece doesn’t have much of a choice. “He’s a very chill kid and doesn’t cry much unless he’s hungry,” Steece, 26, from Lake George, Minn., who works as a teacher in Wuhan, tells TIME. “My biggest fear is that I’ll go out and accidentally transmit the disease to my family.” At 3 a.m. ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized China Infectious Disease onetime overnight Source Type: news
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