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This review describes the principles and process followed to define the target therapeutic ranges for infliximab and adalimumab in the treatment of inflammatory bowel disease.Alimentary Pharmacology &Therapeutics
Publication date: Available online 5 April 2020Source: Journal of Pharmaceutical and Biomedical AnalysisAuthor(s): Katarína Maráková, Juraj Piešťanský, Zuzana Zelinková, Peter Mikuš
You're reading Overcoming Your Former Self: Small Steps Toward Higher Self-Esteem, originally posted on Pick the Brain | Motivation and Self Improvement. If you're enjoying this, please visit our site for more inspirational articles. When analyzing the driving factor behind your decisions, there is one common denominator that many people overlook: self-esteem. Self-esteem is a reflection of your perceived value. If you do not have a positive self-image, your motivation to achieve great things diminishes. Because of this, it is important to work on empowering yourself to better actionize your goals. People suffering fro...
Publication date: Available online 4 April 2020Source: IJC Heart &VasculatureAuthor(s): Thomas H. Schindler, David L. Brown, Justin S. Sadhu
Publication date: Available online 5 April 2020Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Alexandre Joosten, Sean Coeckelenbergh, Brenton Alexander, Maxime Cannesson, Joseph Rinehart
Publication date: Available online 4 April 2020Source: Anaesthesia Critical Care &Pain MedicineAuthor(s): Federico Linassi, Eleonora Maran, Matthias Kreuzer, Paolo Zanatta, Michele Carron
Discussion The embryonic mesoderm forms the skeletal system. The mesoderm is further divided into the dorsal, sclerotome and ventral dermatome. The sclerotome forms the ribs which are under the influence of various genes and growth factors. Congenital rib abnormalities occur in number ( the normal 12 ribs) or in formation/structural. Malformations can include hypoplastic, bridging, forked, fused and hypoplastic ribs. Even ribs with holes occur because of the segmentation issues. Illustrated examples can be found here. The rib’s cartilage, bone or both can be affected. Location along the rib is also variable. Abnormal...
Publication date: Available online 5 April 2020Source: Journal of Psychiatric ResearchAuthor(s): Chengchao Zuo, Huan Cao, Fengfei Ding, Jianling Zhao, Yaqi Huang, Guo Li, Shanshan Huang, Hong Jiang, Yongsheng Jiang, Furong Wang
Publication date: Available online 5 April 2020Source: Journal of Psychiatric ResearchAuthor(s): Christian Eric Deuter, Katja Wingenfeld, Christian Otte, Jasmin Bustami, Michael Kaczmarczyk, Linn Kristina Kuehl
Authors: Pu M, Wang X, Zhang J Abstract An increasing body of research has focused on the functions of the glutamate receptor ionotropic kainate 4 (GRIK4) gene in treatment for depression, memory, as well as neurodegenerative diseases. It is widely recognized that major depressive disorder (MDD) patients often display cognitive dysfunctions, which do not strictly correlate with the severity of depressive symptoms, and in some individuals persist after clinical remission. However, little is known regarding the particular role of GRIK4 in cognitive functions of patients suffering from a MDD. The current study therefo...