Insulin Receptor-Mediated Signaling Regulates Pluripotency Markers and Lineage Differentiation

ConclusionWe report, for the first time to our knowledge, the phosphoproteome of insulin, IGF1, and LIF stimulation in mouse iPSCs to reveal the importance of insulin receptor signaling for the maintenance of pluripotency and lineage determination.Graphical abstract
Source: Molecular Metabolism - Category: Endocrinology Source Type: research