Role of Methylglyoxal in Diabetic Cardiovascular and Kidney Diseases: Insights from Basic Science for Application into Clinical Practice.

CONCLUSION: Reducing MG levels directly using scavengers or indirectly via activation of Nrf2/Glo1 may serve as a novel and potent therapeutic strategy to counter the deleterious effects of MG in diabetic complications.
PMID: 30179128 [PubMed - as supplied by publisher]

Source: Current Pharmaceutical Design - September 3, 2018 Category: Drugs & Pharmacology Authors: Sankaralingam S, Ahmed A, Rahman M, Eid AH, Munusamy S Tags: Curr Pharm Des Source Type: research