Sex-specific risk factors for cardiovascular disease in women-making cardiovascular disease real

Purpose of review Sex-specific differences in pathophysiology, prevalence, and impact of cardiovascular disease (CVD) risk factors may explain the high cardiovascular mortality rates in women. Recent findings We review the sex differences in traditional risk factors (dyslipidemia, hypertension, diabetes, and smoking) and nontraditional risk factors (menopause and hormones, pregnancy, inflammation and autoimmune diseases, anemia, depression, and migraines) and their prognostic and therapeutic implications. Summary Recent research indicates that with respect to traditional risk factors such as dyslipidemia, hypertension, diabetes, and smoking, women appear to have a similar risk of CVD when compared to men. The risk is accelerated after menopause, possibly because of vascular and lipid profile changes. Pregnancy offers a unique opportunity and window to screen otherwise healthy women who may be at an increased risk of CVD in the future. Clinicians should be aware of other novel risk factors including inflammation, anemia, migraines, and depression, and further studies are warranted in order to identify therapeutic implications for these conditions and CVD risk.
Source: Current Opinion in Cardiology - Category: Cardiology Tags: PREVENTION: Edited by Andrew Pipe Source Type: research

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CONCLUSIONS: A minority of pregnant women met the recommended GWG. No difference was noted between normal and high-risk pregnancies. High-risk population tended to have a less healthy lifestyle. Counseling to follow a healthy, balanced diet should be recommended, regardless of pregnancy risk, with particular attention to women at high risk of extra weight gain. PMID: 30109788 [PubMed - in process]
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
CONCLUSIONS: Iron cessation in chronic hemodialysis patients with high ferritin levels did not affect hemoglobin level or ESA dose and can be considered as a safe policy for attenuating the risk of chronic iron overload. PMID: 30109787 [PubMed - in process]
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
Publication date: Available online 16 August 2018Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Chen Chi, Dong-Jie Li, Yu-Jie Jiang, Jie Tong, Hui Fu, Yi-Hang Wu, Fu-Ming ShenAbstractAging is a worldwide challenge, and it is accompanied by the accumulation of senescent cells. Cellular senescence is traditionally defined as permanent cell growth arrest and currently includes the senescence-associated secretory phenotype (SASP). There are two main types of cellular senescence, including telomere-dependent replicative senescence and stress-induced premature senescence. The process of cellul...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
For decades, Tim Lennon repressed memories of the childhood abuse he says he suffered at the hands of a priest. It wasn’t until 1995, when Lennon was in his late 40s and living in San Francisco, that he stumbled across information about clergy sexual abuse and felt decades-old memories come flooding back. “I said, ‘Oh my god, that happened to me,'” Lennon remembers. But even that moment, he says, didn’t prepare him for the memories that resurfaced in 2010 — an avalanche that he believes was triggered by his twin daughters turning 12, the age around which he says he was raped by a priest....
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized healthytime Mental Health/Psychology onetime Source Type: news
In this study, we tested whether catalpol has the potential to improve insulin sensitivity by augmenting myogenesis.Main methodsWe examined the hypoglycaemic mechanism of catalpol in db/db mice and C2C12 cells. db/db mice were treated with catalpol (200 mg/kg) for 8 consecutive weeks. Serum analysis, skeletal muscle performance and histology, and gene and protein expression were performed. In vitro glucose uptake, gene and protein expression were determined, and small interfering RNA was used to identify the underlying hypoglycaemic mechanism of catalpol.Key findingsIn this study, we tested whether catalpol has the poten...
Source: Life Sciences - Category: Biology Source Type: research
This study explores the in-situ precipitation of scorodite (FeAsO4.2H2O) during the atmospheric enargite leaching in acid chloride media. The temperature, oxygen sparging rate and the different fractions of the catalyst and ferric ions were the effective parameters on the scorodite precipitation process. Crystalline scorodite was precipitated out of the leach solution in the absence of seed at temperatures above 80 °C where the ratio of both AF5 to concentrate and activated carbon (AC) to concentrate were 1:2 and 1:1, respectively. The minimal dosage of ferric ions to form the scorodite residue was 5 g/L....
Source: Journal of Hazardous Materials - Category: Environmental Health Source Type: research
People with type 2 diabetes can significantly reduce cardiovascular disease risk with proper treatment and not smoking, according to a study in Sweden.
Source: Health News - - Category: Consumer Health News Source Type: news
Publication date: Available online 16 August 2018Source: Revista Clínica Española (English Edition)Author(s): J. Montes-Santiago
Source: Revista Clinica Espanola - Category: Internal Medicine Source Type: research
CONCLUSION: The relationship between depressive symptoms and untreated coronal dental caries failed to remain significant after the addition of tobacco usage in the analysis. PMID: 30106522 [PubMed - as supplied by publisher]
Source: Community Dental Health - Category: Dentistry Tags: Community Dent Health Source Type: research
Resumo O objetivo deste artigo é medir a prevalência e identificar fatores associados à dor lombar intensa (DL intensa) entre parturientes do município de Rio Grande, RS, Brasil, em 2013. Questionário padronizado aplicado por entrevistadoras previamente treinadas em até 48 horas após o parto. Realizou-se análise multivari ável utilizando regressão de Poisson tendo a razão de prevalência como medida de efeito. Dentre as 2685 parturientes incluídas no estudo, 51,2% referiram dor lombar gestacional e 27,3% tinham DL intensa, com maior pro...
Source: Ciencia e Saude Coletiva - Category: Occupational Health Source Type: research
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