Sulfonylurea receptor 1 expression is variable in adult and pediatric brain tumors.
CONCLUSION: SUR1 is a putative therapeutic target to reduce neuroinflammation in adult and pediatric brain tumors. Inhibition of SUR1 may result in neuronal stabilization in glioblastoma, cerebral metastases, and posterior fossa ependymoma and reduced edema in medulloblastoma.
.
PMID: 30079884 [PubMed - as supplied by publisher]
Source: Clinical Neuropathology - Category: Pathology Authors: Thompson EM, Halvorson K, McLendon R Tags: Clin Neuropathol Source Type: research
More News: Brain | Brain Cancers | Brain Tumor | Children | Corticosteroid Therapy | Ependymoma | Glyburide | Hemorrhagic Stroke | Medulloblastoma | Neurology | Pathology | Pediatrics | Stroke | Study | Subarachnoid Hemorrhage